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特应性皮炎局部糖皮质激素和钙调磷酸酶抑制剂治疗的临床方面-一项初步问卷调查研究。

Clinical aspects of the treatment of atopic dermatitis with topical glucocorticoids and calcineurin inhibitors - a pilot questionnaire study.

机构信息

University Hospital, Kraków, Poland.

Department of Dermatology, Jagiellonian University Medical College, Kraków, Poland.

出版信息

Folia Med Cracov. 2023 Apr 30;63(1):97-108. doi: 10.24425/fmc.2023.145433.

DOI:10.24425/fmc.2023.145433
PMID:37406280
Abstract

Atopic dermatitis (AD) is the most common inflammatory skin disease. However, recent reports concerning the simple clinical aspects of treatment with topical glucocorticosteroids (TCS) and calcineurin inhibitors (TCI) are lacking. The objective of this study is providing an update on these characteristics of AD management. A group of 150 adults suffering from AD treated with TCS during last year was asked to fill an anonymous questionnaire. The course of topical treatment was analyzed in the context of the severity of symptoms and the knowledge of the patients about therapy. During the last year, the majority of patients (66%) were treated with class IV TCS; however, in the last two weeks, class I TCS was used the most frequently (35%). Only 11% were familiar with the concept of intermittent therapy and 4% used the fingertip unit (FTU). In total, 77% of them used TCI. Most of the patients used the same class of TCS permanently. Unfortunately, patients are unaware of simple approaches (like intermittent therapy or FTU) that increase both the effectiveness and safety of the treatment. Practicians should be aware of these problems to identify and eliminate them, primarily through the education of patients.

摘要

特应性皮炎(AD)是最常见的炎症性皮肤病。然而,最近关于外用糖皮质激素(TCS)和钙调磷酸酶抑制剂(TCI)治疗的简单临床方面的报告较少。本研究的目的是提供 AD 管理这些特征的最新信息。我们要求去年接受 TCS 治疗的 150 名成人 AD 患者填写一份匿名问卷。根据症状的严重程度和患者对治疗的了解,分析了局部治疗的过程。在过去的一年中,大多数患者(66%)接受了 IV 级 TCS 治疗;然而,在过去的两周中,最常使用 I 级 TCS(35%)。只有 11%的患者了解间歇性治疗的概念,4%的患者使用指尖单位(FTU)。总的来说,77%的患者使用了 TCI。他们中的大多数人长期使用同一种 TCS。不幸的是,患者不知道简单的方法(如间歇性治疗或 FTU),这些方法可以提高治疗的有效性和安全性。临床医生应该意识到这些问题,并通过对患者的教育来识别和消除这些问题。

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