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大五人格特质能否预测中老年人群临床诊断慢性支气管炎的发病几率及7年患病风险?

Can the Big Five personality traits predict ever chance and 7-year risk of clinically diagnosed chronic bronchitis in middle-aged and older adults?

作者信息

Kang Weixi, Malvaso Antonio

机构信息

UK DRI Care Research and Technology Centre, Department of Brain Sciences, Imperial College London, United Kingdom.

Department of Brain and Behavioral Sciences, University of Pavia, Italy.

出版信息

J Psychosom Res. 2023 Sep;172:111423. doi: 10.1016/j.jpsychores.2023.111423. Epub 2023 Jun 28.

Abstract

OBJECTIVE

Chronic bronchitis refers to a chronic condition that is characterized by long-term inflammation of the bronchi. It is of great importance to understand the contributing risk factors for chronic bronchitis because it is associated with adverse outcomes such as healthcare burden and mortality. We aimed to understand if the personality traits could predict ever and the 7-year risk of clinically diagnosed chronic bronchitis in a large cohort of participants from the UK.

METHODS

We analyzed data from Understanding Society: the UK Household Longitudinal Study, which consists of 15,387 middle-aged or older participants for the cross-sectional analysis and 8783 middle-aged or older adults for the longitudinal analysis using two binary logistic regressions.

RESULTS

We found that Neuroticism (OR = 1.36, p < 0.001, 95% C.I. [1.23, 1.51]), Conscientiousness (OR = 0.87, p = 0.014, 95% C.I. [0.78, 0.97]), and Extraversion (OR = 1.15, p = 0.009, 95% C.I. [1.04, 1.29]) are related to a higher chance of ever clinically diagnosed chronic bronchitis. However, Agreeableness and Openness were not related to the chance of ever clinically diagnosed chronic bronchitis. Moreover, Conscientiousness (OR = 0.72, p = 0.012, 95% C.I. [0.55, 0.93]) was related to a lower risk of future clinical diagnosis of chronic bronchitis whereas Extraversion (OR = 1.35, p = 0.024, 95% C.I. [1.04, 1.76]) was associated with a higher risk of future chronic bronchitis. However, Neuroticism, Agreeableness, and Openness were not related to change of ever clinically diagnosed chronic bronchitis.

CONCLUSION

We showed that personality can identify people who are at greater risk of chronic bronchitis, which has translational utility for healthcare of middle-aged and older adults.

摘要

目的

慢性支气管炎是一种以支气管长期炎症为特征的慢性疾病。了解慢性支气管炎的促成风险因素非常重要,因为它与医疗负担和死亡率等不良后果相关。我们旨在了解人格特质是否能预测来自英国的一大群参与者中临床诊断慢性支气管炎的既往情况及7年患病风险。

方法

我们分析了来自“理解社会”(英国家庭纵向研究)的数据,该研究包括15387名中年或老年参与者用于横断面分析,以及8783名中年或老年成年人用于纵向分析,采用了两个二元逻辑回归。

结果

我们发现神经质(优势比=1.36,p<0.001,95%置信区间[1.23, 1.51])、尽责性(优势比=0.87,p=0.014,95%置信区间[0.78, 0.97])和外向性(优势比=1.15,p=0.009,95%置信区间[1.04, 1.29])与临床诊断慢性支气管炎的既往患病几率较高相关。然而,宜人性和开放性与临床诊断慢性支气管炎的既往患病几率无关。此外,尽责性(优势比=0.72,p=0.012,95%置信区间[0.55, 0.93])与未来临床诊断慢性支气管炎的风险较低相关,而外向性(优势比=1.35,p=0.024,95%置信区间[1.04, 1.76])与未来慢性支气管炎的风险较高相关。然而,神经质、宜人性和开放性与临床诊断慢性支气管炎既往情况的变化无关。

结论

我们表明人格可以识别出患慢性支气管炎风险更高的人群,这对中老年成年人的医疗保健具有转化应用价值。

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