非裔美国人葡萄膜黑色素瘤：诊断挑战。

Uveal melanoma in African Americans: Diagnostic challenges.

机构信息

Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland, OH, USA.

Department of Anatomic Pathology, R. Tomsich Pathology & Laboratory Medicine Institute, Cleveland, OH, USA.

出版信息

Surv Ophthalmol. 2024 Mar-Apr;69(2):190-197. doi: 10.1016/j.survophthal.2023.06.011. Epub 2023 Jul 3.

DOI:10.1016/j.survophthal.2023.06.011

PMID:37406779

Abstract

Uveal melanoma (UM) is uncommon in African Americans. Owing to its rarity, UM may not be suspected in African Americans leading to delayed diagnosis. In addition, socioeconomic factors may also play a role in delayed diagnosis. Clinical and ultrasonographic features may be atypical due to racial pigmentation, necessitating diagnostic fine needle aspiration biopsy. Herein, we report an illustrative case series of 12 African Americans with UM highlighting clinical features and diagnostic challenges.

摘要

葡萄膜黑色素瘤（UM）在非裔美国人中较为罕见。由于其罕见性，UM 在非裔美国人中可能不会被怀疑，导致诊断延迟。此外，社会经济因素也可能在诊断延迟中发挥作用。由于种族色素沉着，临床和超声特征可能不典型，需要进行诊断性细针抽吸活检。在此，我们报告了 12 例非裔美国人 UM 的病例系列，重点介绍了临床特征和诊断挑战。