Department of Ophthalmology, Barzilai University Medical Center, Ashkelon, Israel.
Goldschleger Eye Institute, Sheba Medical Center, Ramat Gan, Israel.
J Med Case Rep. 2023 Jul 6;17(1):309. doi: 10.1186/s13256-023-04003-y.
Eales' disease is an idiopathic peripheral retinal vasculopathy characterized by retinal phlebitis, ischemia, retinal neovascularization, and recurrent vitreous hemorrhages. But CRAO is an unusual presentation.
A 27-year-old healthy female nurse of Indian descent presented with sudden vision loss in her right eye upon awakening. Central retinal artery occlusion (CRAO), combined with mild central retinal vein occlusion (CRVO), was diagnosed. During the second of three consecutive sessions of hyperbaric oxygen treatments, her vision rapidly improved. One week later, she developed peripheral phlebitis in the same eye. Infectious, inflammatory, and hematologic etiologies were excluded. The systemic evaluation was normal except for a positive Mantoux tuberculin skin test. Following systemic steroidal treatment, she experienced gradual improvement of her vasculitis. Two weeks later, mild retinal phlebitis appeared in her left eye. Eales' disease was diagnosed after the exclusion of other diseases.
This is an unusual Eales' disease case, which presented as combined CRAO with mild CRVO. The association of CRAO and Eales' disease is reported here for the first time, to our best knowledge.
Eales 病是一种特发性周边视网膜血管病变，其特征为视网膜静脉炎、缺血、视网膜新生血管形成和复发性玻璃体积血。但 CRAO 是一种不常见的表现。
一位 27 岁的印度裔健康女护士，醒来时发现右眼突然失明。诊断为中央视网膜动脉阻塞（CRAO）合并轻度中央视网膜静脉阻塞（CRVO）。在三次连续高压氧治疗中的第二次治疗后，她的视力迅速改善。一周后，她的同一只眼出现了外周静脉炎。排除了感染、炎症和血液系统等病因。除了结核菌素皮肤试验阳性外，全身评估正常。在进行全身类固醇治疗后，她的血管炎逐渐好转。两周后，她的左眼出现轻度视网膜静脉炎。排除其他疾病后，诊断为 Eales 病。
这是一个不寻常的 Eales 病病例，表现为 CRAO 合并轻度 CRVO。据我们所知，这是首次报告 CRAO 和 Eales 病之间的关联。
