Mage P, Ballanger P, Lakdja F, Guibert J L, Vincent J, Chomy P, Lamarche P
Ann Urol (Paris). 1986;20(4):271-4.
The authors report two cases of spontaneous regression of pulmonary metastases from hypernephroma; this is an exceptional event that occurs in 0.8% of metastasized renal carcinomas; spontaneous regression in all cancers as a group occurs in 0.0014% of cases. The theories postulated up till now to explain this phenomenon are unconvincing. The authors suggest the possibility of tumorous emboli: this event, that occurs mainly in those carcinomas with a propensity for extension to veins, such as renal carcinoma, choriocarcinoma, hepatoma and liver metastases, does not necessarily give rise to a metastasis. The evidence that leads to advocate nephrectomy in metastasized renal carcinoma are recalled and discussed.
作者报告了两例肾细胞癌肺转移灶自发消退的病例;这是一种罕见事件,在0.8%的转移性肾癌中发生;在所有癌症中,这种自发消退现象总体发生率为0.0014%。迄今为止提出的用以解释这一现象的理论都缺乏说服力。作者提出了肿瘤栓子的可能性:这种情况主要发生在那些易于侵犯静脉的癌症中,如肾癌、绒毛膜癌、肝癌及肝转移癌,但不一定会导致转移。文中回顾并讨论了支持对转移性肾癌进行肾切除术的证据。