Miyamoto T, Mihara M, Hagari Y, Shimao S, Nakahara T, Kimura M
Arch Dermatol. 1986 Aug;122(8):915-8.
We encountered a patient with infantile digital fibromatosis. The representative lesion was a firm, indurated nodule, which developed in the scar of a previous injury on the skin of the left thigh of an 11-year-old girl. Electron microscopy revealed tumor cells that were strongly reminiscent of myofibroblasts. Histopathologically, the cytoplasmic inclusion bodies in the tumor cells stained positively or negatively with hematoxylin-eosin. Electron microscopically, they were either well-defined dense bodies that often showed a doughnutlike appearance or ill-demarcated dense bodies. Spotty calcified foci were seen in the central area of the tumor mass.
我们遇到了一名患有婴儿指纤维瘤病的患者。典型病变为一个坚实、硬结的结节，发生于一名11岁女孩左大腿皮肤先前损伤的瘢痕处。电子显微镜检查显示肿瘤细胞强烈提示为肌成纤维细胞。组织病理学上，肿瘤细胞中的胞质包涵体苏木精-伊红染色呈阳性或阴性。电子显微镜下，它们要么是界限清晰、常呈甜甜圈样外观的致密小体，要么是界限不清的致密小体。在肿瘤块的中央区域可见散在钙化灶。
