Frizziero L, Zizzi F, Leghissa R, Ferruzzi A
Ann Rheum Dis. 1986 Jul;45(7):529-33. doi: 10.1136/ard.45.7.529.
The microhysteroscope, which affords direct in vivo observation of otherwise inaccessible surfaces, can be used to great advantage in arthroscopy. Although conventional arthroscopy can distinguish between 'inflammatory' and 'reactive' (post-traumatic) synovial changes, the microendoscope offers the possibility of more precise differentiation. Synovial membranes, joint cartilage, and menisci were studied at four different magnifications, including microscopic observation of vitally stained cells. Frankly pathological synovia (e.g., rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis) were compared and distinguished from examples of less florid synovial changes. The fibrocartilaginous structure of the menisci and secondary undulations and tertiary depression of joint cartilage become visible in vivo with the microendoscope; these may well point to early damage to these structures. The authors believe that the three dimensional images at the magnifications provided by this microendoscope go some way towards bridging the gap between the conventional arthroscope, the light microscope, and the scanning electron microscope. This report presents preliminary findings with this new technique.
微型宫腔镜能够对原本无法触及的表面进行直接的体内观察，在关节镜检查中具有很大的优势。尽管传统关节镜检查能够区分“炎症性”和“反应性”（创伤后）滑膜变化，但微型内窥镜提供了更精确区分的可能性。我们在四种不同放大倍数下对滑膜、关节软骨和半月板进行了研究，包括对活体染色细胞的显微镜观察。对明显病理性的滑膜（如类风湿性关节炎、银屑病关节炎、强直性脊柱炎）进行了比较，并与滑膜变化较轻的例子进行了区分。通过微型内窥镜可以在体内看到半月板的纤维软骨结构以及关节软骨的二级波动和三级凹陷；这些很可能表明这些结构早期受到了损伤。作者认为，这种微型内窥镜所提供放大倍数下的三维图像在一定程度上弥合了传统关节镜、光学显微镜和扫描电子显微镜之间的差距。本报告展示了这项新技术的初步研究结果。
