Department of Orthopaedic Surgery, Keck School of Medicine of the University of Southern California, 1520 San Pablo Street, Suite 2000, Los Angeles, CA, 90033-5322, USA.
Department of Orthopedics and Sports Medicine, University of Washington, Seattle, WA, USA.
Eur J Orthop Surg Traumatol. 2024 Oct;34(7):3473-3481. doi: 10.1007/s00590-023-03633-8. Epub 2023 Jul 6.
Obesity remains a global epidemic. The effect of obesity on the risk of complications after acetabular fracture is unknown. Here, we evaluate the effect of BMI on early complications and mortality after acetabular fracture. We hypothesize that the risk of inpatient complications and mortality will be greater in patients with high BMI when compared to those with normal BMI.
Adult patients with acetabular fracture were identified via the Trauma Quality Improvement Program data from 2015 to 2019. The primary outcome was overall complication rate with reference to normal-weight patients (BMI = 25-30 kg/m). The secondary outcome was rates of death. The association of obesity class on the primary and secondary outcomes was assessed using Bonferroni-corrected multiple logistic regression models considering patient, injury, and treatment covariates.
A total of 99,721 patients with acetabular fracture were identified. Class I obesity (BMI = 30-35 kg/m) was associated with 1.2 greater adjusted relative risk (aRR; 95% confidence interval (CI) 1.1-1.3) of any adverse event, without significant increases in adjusted risk of death. Class II obesity (BMI = 35-40 kg/m) was associated with aRR = 1.2 (95% CI 1.1-1.3) of any adverse event and aRR = 1.5 (95% CI 1.2-2.0) of death. Class III obesity (BMI ≥ 40 kg/m) was associated with aRR = 1.3 (95% CI 1.2-1.4) of any adverse event and aRR = 2.3 (95% CI 1.8-2.9) of death.
Obesity is associated greater risk of adverse events and death following acetabular fracture. Obesity severity classification scales with these risks.
肥胖仍是全球性的流行疾病。肥胖对髋臼骨折后并发症风险的影响尚不清楚。在此,我们评估 BMI 对髋臼骨折患者早期并发症和死亡率的影响。我们假设与正常 BMI 患者相比,高 BMI 患者的住院并发症和死亡率风险更大。
通过 2015 年至 2019 年创伤质量改进计划的数据,确定髋臼骨折的成年患者。主要结果是参考正常体重患者(BMI=25-30kg/m)的总体并发症发生率。次要结果是死亡率。使用经 Bonferroni 校正的多元逻辑回归模型,考虑患者、损伤和治疗因素,评估肥胖等级对主要和次要结果的关联。
共确定了 99721 例髋臼骨折患者。I 级肥胖(BMI=30-35kg/m)的调整后相对风险(aRR;95%置信区间(CI)为 1.1-1.3)增加 1.2,任何不良事件的调整风险无显著增加。II 级肥胖(BMI=35-40kg/m)与 aRR=1.2(95%CI 1.1-1.3)的任何不良事件和 aRR=1.5(95%CI 1.2-2.0)的死亡率相关。III 级肥胖(BMI≥40kg/m)与 aRR=1.3(95%CI 1.2-1.4)的任何不良事件和 aRR=2.3(95%CI 1.8-2.9)的死亡率相关。
肥胖与髋臼骨折后不良事件和死亡风险增加相关。肥胖严重程度分类与这些风险相关。