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心力衰竭各阶段在一般人群中的流行情况及其对心力衰竭预防的影响:来自 2012-2015 年中国高血压调查的报告。

Prevalence of heart failure stages in the general population and implications for heart failure prevention: reports from the China Hypertension Survey 2012-15.

机构信息

Department of Cardiology, Hypertension Research Laboratory, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, No.106, Zhongshan 2nd Road, Yuexiu District, Guangzhou 510080, China.

Division of Prevention and Community Health, National Center for Cardiovascular Disease, Fuwai Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, No. 15 (Lin), Fengcunxili, Mentougou District, Beijing 102308, China.

出版信息

Eur J Prev Cardiol. 2023 Sep 20;30(13):1391-1400. doi: 10.1093/eurjpc/zwad223.

DOI:10.1093/eurjpc/zwad223
PMID:37410587
Abstract

AIMS

There are no nationwide epidemiological data on heart failure (HF) stages in China. Knowledge of the prevalence of HF stages is crucial for planning HF prevention and management strategies. We aimed to evaluate the prevalence of HF stages in the general Chinese population and the specific prevalence by age, sex, and urbanity.

METHODS AND RESULTS

This is a cross-sectional study and national representative general population aged ≥ 35 years (n = 31 494, mean age 57.4 years, women 54.1%) were obtained from the China Hypertension Survey. Participants were divided into Stage A (at-risk for HF), Stage B (pre-HF), and Stage C (symptomatic HF). Survey weights were calculated based on the 2010 China population census data. The prevalence of Stage A was 35.8% (≈245.1 million), Stage B 42.8% (≈293.1 million), and Stage C 1.1% (≈7.5 million). The prevalence of Stages B and C increased with increasing age (P < 0.0001). Women had lower prevalence of Stage A (32.6% vs. 39.3%; P < 0.0001) but higher prevalence of Stage B (45.9% vs. 39.5%; P < 0.0001) than men. People from rural area had lower prevalence of Stage A (31.9% vs. 41.0%; P < 0.0001) but higher prevalence of Stage B (47.8% vs. 36.2%; P < 0.0001) than people from urban. The prevalence of Stage C was similar by sex and urbanity.

CONCLUSION

The burdens of pre-clinical and clinical HF are high and vary by age, sex, and urbanity in China. Targeted interventions are needed to reduce the high burden of pre-clinical and clinical HF.

摘要

目的

中国尚无心力衰竭(HF)分期的全国性流行病学数据。了解 HF 分期的流行情况对于规划 HF 预防和管理策略至关重要。本研究旨在评估中国一般人群中 HF 分期的流行情况,以及按年龄、性别和城市程度划分的特定流行情况。

方法和结果

这是一项横断面研究,从中国高血压调查中获得了≥35 岁的全国代表性一般人群(n=31494 人,平均年龄 57.4 岁,女性占 54.1%)。参与者被分为 A 期(HF 风险期)、B 期(HF 前期)和 C 期(HF 症状期)。根据 2010 年中国人口普查数据计算了调查权重。A 期的患病率为 35.8%(约 2.451 亿),B 期为 42.8%(约 2.931 亿),C 期为 1.1%(约 750 万)。B 期和 C 期的患病率随年龄增长而增加(P<0.0001)。女性 A 期的患病率较低(32.6% vs. 39.3%;P<0.0001),B 期的患病率较高(45.9% vs. 39.5%;P<0.0001)。农村地区人群 A 期的患病率较低(31.9% vs. 41.0%;P<0.0001),B 期的患病率较高(47.8% vs. 36.2%;P<0.0001)。B 期的患病率在性别和城市程度方面差异无统计学意义。

结论

中国人群中临床前和临床 HF 的负担较高,且随年龄、性别和城市程度而异。需要采取有针对性的干预措施来降低临床前和临床 HF 的高负担。

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