Gvamichava R L, Khomeriki S G, Morozov I A
Arkh Patol. 1986;48(5):35-42.
All types of endocrine cells that occur in healthy persons were identified in the mucous membrane of gastric antrum of patients with obesity. Ultrastructural changes in endocrine cells in obese patients are suggestive of degenerative processes: in D-, D1- and G-cells these are fatty, P- and EC-cells albuminoid. Endocrine cells containing granules characteristic for cells of several types were found more frequently than in control patients. However such mixed types were observed in the two above groups of endocrine cells. Infiltration of mucous membrane of gastric antrum with lymphocytes and activation of intraepithelial lymphocytes and their interaction with endocrine cells were more pronounced in obese patients.
在肥胖患者胃窦黏膜中识别出了健康人所具有的所有类型的内分泌细胞。肥胖患者内分泌细胞的超微结构变化提示存在退行性过程：在D细胞、D1细胞和G细胞中表现为脂肪变性，在P细胞和EC细胞中表现为蛋白样变性。发现含有几种类型细胞特征性颗粒的内分泌细胞比对照组患者更为常见。然而，上述两组内分泌细胞中均观察到了这种混合类型。肥胖患者胃窦黏膜的淋巴细胞浸润、上皮内淋巴细胞的活化及其与内分泌细胞的相互作用更为明显。
