Liu Kai, Liu Xuexue, Chen Jian, Wang Xingli, Zhang Weiguo
College of Mechanical and Electronic Engineering, Northwest A&F University, Yangling, Shaanxi, 712100, People's Republic of China.
Nanotechnology. 2023 Jul 24;34(41). doi: 10.1088/1361-6528/ace4d3.
Dendritic fibrous nano silica (DFNS) represents an optimal carrier material for pesticide constituents, due to its radial accessibility channels and high specific surface area. A low-energy methodology for synthesizing DFNS at a low volume ratio of oil to water is provided by employing 1-pentanol as the oil solvent in the microemulsion synthesis system, renowned for its remarkable stability and exceptional solubility. The DFNS@KM nano-pesticide was fabricated using a diffusion supported loading (DiSupLo) method and kresoxim-methyl (KM) as the template drug. Findings from Fourier-transform infrared spectroscopy, XRD, thermogravimetric, differential thermal analysis, and Brunauer-Emmet-Teller analyzes revealed the physical adsorption of KM onto the synthesized DFNS without any chemical bonding, with KM mainly existing in an amorphous state within the channels. High-performance liquid chromatography measurements demonstrated that only the loading amount of DFNS@KM was primarily dependent on the KM to DFNS ratio, with minimal effects observed from loading temperature and time. The loading amount and encapsulation efficiency of DFNS@KM were found to be 63.09% and 84.12%, respectively. Furthermore, DFNS effectively prolonged the release of KM, with a cumulative release rate of 85.43% over 180 h. The successful loading of pesticide components into DFNS synthesized with a low oil-to-water ratio provides theoretical support for the industrialization of nano-pesticides, with significant implications for enhancing pesticide utilization, reducing pesticide dosage, augmenting agricultural efficiency, and promoting sustainable agricultural development.
树枝状纤维纳米二氧化硅（DFNS）因其径向可及通道和高比表面积，是农药成分的理想载体材料。在微乳液合成体系中，采用1-戊醇作为油相溶剂，提供了一种在低油水体积比下合成DFNS的低能耗方法，该体系以其卓越的稳定性和非凡的溶解性而闻名。以嘧菌酯（KM）为模板药物，采用扩散支持负载（DiSupLo）法制备了DFNS@KM纳米农药。傅里叶变换红外光谱、XRD、热重、差热分析和布鲁诺尔-埃米特-泰勒分析结果表明，KM在合成的DFNS上发生物理吸附，无化学键合，KM主要以无定形状态存在于通道内。高效液相色谱测量表明，只有DFNS@KM的负载量主要取决于KM与DFNS的比例，负载温度和时间的影响最小。DFNS@KM的负载量和包封率分别为63.09%和84.12%。此外，DFNS有效地延长了KM的释放，180 h内累积释放率为85.43%。将农药成分成功负载到低油水比合成的DFNS中，为纳米农药的工业化提供了理论支持，对提高农药利用率、降低农药用量、提高农业效率和促进可持续农业发展具有重要意义。
