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无风险因素的甲状腺危象:一例报告

Thyrotoxic Crisis in the Absence of Risk Factors: A Case Report.

作者信息

Reddy Gowry, Livingston Jonathan, Gandhi Darshan, Sumrein Fadwa

机构信息

Internal Medicine, New York Medical College at St. Mary's General Hospital, Passaic, USA.

Internal Medicine, New York Medical College at St. Clare's Health, Denville, USA.

出版信息

Cureus. 2023 Jun 5;15(6):e39972. doi: 10.7759/cureus.39972. eCollection 2023 Jun.

DOI:10.7759/cureus.39972
PMID:37416045
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10321309/
Abstract

Thyrotoxic crisis is a severe, life-threatening form of thyrotoxicosis characterized by elevated circulating thyroid hormone that can lead to profound complications. Early diagnostic interventions include a thorough physical examination, laboratory assessments of thyroid hormone levels, and the utilization of quantifying assessment tools to grade the severity of the condition. A targeted therapeutic regimen involving a combination of thioamides, beta-blocking agents, and iodide therapies is administered to combat each stage of the physiological process involved in a thyroid storm. The prompt recognition of clinical manifestations and systemic complications of thyrotoxic crisis is of paramount significance to prevent therapeutic delay and reduce patient mortality. Here, we report an atypical case of a new-onset thyrotoxic crisis in a patient without apparent underlying predisposing factors.

摘要

甲状腺危象是一种严重的、危及生命的甲状腺毒症形式,其特征是循环甲状腺激素升高,可导致严重并发症。早期诊断干预措施包括全面的体格检查、甲状腺激素水平的实验室评估,以及使用量化评估工具对病情严重程度进行分级。采用包括硫代酰胺、β受体阻滞剂和碘剂治疗在内的靶向治疗方案,以应对甲状腺风暴所涉及的生理过程的每个阶段。迅速识别甲状腺危象的临床表现和全身并发症对于防止治疗延误和降低患者死亡率至关重要。在此,我们报告一例无明显潜在诱发因素的新发甲状腺危象非典型病例。

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1
Thyrotoxic Crisis in the Absence of Risk Factors: A Case Report.无风险因素的甲状腺危象:一例报告
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本文引用的文献

1
National Trends in Incidence, Mortality, and Clinical Outcomes of Patients Hospitalized for Thyrotoxicosis With and Without Thyroid Storm in the United States, 2004-2013.美国 2004-2013 年因甲状腺毒症住院患者(伴与不伴甲状腺危象)的发病率、死亡率和临床结局的全国趋势。
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Diagnosis and management of thyrotoxicosis.甲状腺毒症的诊断与管理
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3
Life-threatening thyrotoxicosis. Thyroid storm.危及生命的甲状腺毒症。甲状腺危象。
Endocrinol Metab Clin North Am. 1993 Jun;22(2):263-77.
4
The influence of hyperthyroidism and hypothyroidism on alpha- and beta-adrenergic receptor systems and adrenergic responsiveness.甲状腺功能亢进和甲状腺功能减退对α-和β-肾上腺素能受体系统及肾上腺素能反应性的影响。
Endocr Rev. 1983 Fall;4(4):378-88. doi: 10.1210/edrv-4-4-378.