Hameed Mohamed Siraj Shahul, Wright Ann, Chern Bernard Su Min
Division of Obstetrics and Gynaecology, Department of Minimally Invasive Surgery, K. K. Women's and Children's Hospital, Singapore.
Division of Obstetrics and Gynaecology, Department of Maternal Fetal Medicine, K. K. Women's and Children's Hospital, Singapore.
Gynecol Minim Invasive Ther. 2023 Apr 19;12(2):64-71. doi: 10.4103/gmit.gmit_116_22. eCollection 2023 Apr-Jun.
The incidence of cesarean scar pregnancy (CSP) is increasing reflecting the global increase in cesarean section (CS) rate which has almost doubled since 2000. CSP differs from other types of ectopic pregnancy in its ability to progress while still carrying a significant risk of maternal morbidity. Little is known about precise etiology or natural history although current interest in the pathology of placenta accretes spectrum disorders might be enlightening. Early detection and treatment of CSP are challenging. Once diagnosed, the recommendation is to offer early termination of pregnancy because of the potential risks of continuing the pregnancy. However, as the likelihood of future pregnancy complications for any CSP varies depending on its individual characteristics, this might not always be necessary nor might it be the patient's preferred choice if she is asymptomatic, hemodynamically stable, and wants a baby. The literature supports an interventional rather than a medical approach but the safest and most efficient clinical approach to CSP in terms of treatment modality and service delivery has yet to be determined. This review aims to provide an overview of CSP etiology, natural history, and clinical implications. Treatment options and methods of CSP repair are discussed. We describe our experience in a large tertiary center in Singapore with around 16 cases/year where most treatment modalities are available as well as an "accreta service" for continuing pregnancies. We present a simple algorithm for approach to management including a method of triaging for those CSPs suitable for minimally invasive surgery.
剖宫产瘢痕妊娠(CSP)的发生率正在上升,这反映了全球剖宫产(CS)率的增加,自2000年以来,剖宫产率几乎翻了一番。CSP与其他类型的异位妊娠不同,它在继续妊娠的同时仍有进展的能力,且存在孕产妇发病的重大风险。尽管目前对胎盘植入谱系疾病病理学的关注可能会带来启发,但对其确切病因或自然病史知之甚少。CSP的早期检测和治疗具有挑战性。一旦确诊,由于继续妊娠存在潜在风险,建议尽早终止妊娠。然而,由于任何CSP未来发生妊娠并发症的可能性因其个体特征而异,如果患者无症状、血流动力学稳定且想要孩子,那么终止妊娠可能并非总是必要的,也可能不是患者的首选。文献支持采用介入而非药物治疗方法,但就治疗方式和服务提供而言,CSP最安全、最有效的临床治疗方法尚未确定。本综述旨在概述CSP的病因、自然病史及临床意义。讨论了CSP的治疗选择和修复方法。我们描述了我们在新加坡一家大型三级中心的经验,该中心每年约有16例病例,提供大多数治疗方式以及针对继续妊娠的“植入服务”。我们提出了一种简单的管理方法算法,包括一种对适合微创手术的CSP进行分诊的方法。