Shah Snehal, Ghosh Soumya, Nagarajan Lakshmi
Dept of Neurology, Perth Children's Hospital, Nedlands, WA 6009, Australia.
Faculty of Health and Medical Sciences, University of Western Australia, Nedlands, WA 6009, Australia.
Epilepsy Behav Rep. 2023 Jun 12;23:100611. doi: 10.1016/j.ebr.2023.100611. eCollection 2023.
Electrical Status epilepticus of sleep (SES) is an EEG pattern where there is significant activation of epileptiform activity in NREM sleep. A spike wave index (SWI) of > 80-85% is often labelled as typical SES. We aimed to explore if sleep during a standard daytime-EEG, as compared an overnight-EEG, was adequate to diagnose ESES. Ten children with daytime and overnight studies suggestive of SES were audited. SWI and Spike Wave Density (SWD) were calculated for 5-minute epochs of wake in the daytime and overnight study, as well daytime-EEG sleep and first and last NREM cycle in the overnight-EEG. SWI in daytime NREM was not significantly different from SWI in the first sleep cycle of the overnight study. SWI in the last sleep cycle was significantly lower than the first sleep cycle in the overnight-EEG. SWD was significantly higher in the first sleep cycle in the overnight-EEG than the daytime sleep and the last NREM cycle. SES may be diagnosed in NREM sleep from a daytime-EEG study. Larger studies are needed to explore the significance of the disparity between SWI and SWD in the first and last NREM cycles in the overnight study.
睡眠期癫痫性电持续状态（SES）是一种脑电图模式，即非快速眼动睡眠期癫痫样活动显著激活。棘波指数（SWI）>80 - 85%通常被标记为典型的SES。我们旨在探讨与整夜脑电图相比，标准日间脑电图检查期间的睡眠是否足以诊断ESES。对10名日间和整夜检查提示为SES的儿童进行了审核。在日间和整夜检查的清醒状态下，以及日间脑电图睡眠和整夜脑电图的第一个和最后一个非快速眼动周期中，计算了5分钟时段的SWI和棘波密度（SWD）。日间非快速眼动睡眠期的SWI与整夜检查第一个睡眠周期的SWI无显著差异。整夜脑电图最后一个睡眠周期的SWI显著低于第一个睡眠周期。整夜脑电图第一个睡眠周期的SWD显著高于日间睡眠和最后一个非快速眼动周期。SES可通过日间脑电图检查在非快速眼动睡眠期进行诊断。需要更大规模的研究来探讨整夜检查中第一个和最后一个非快速眼动周期SWI和SWD差异的意义。
