睡眠与癫痫：知识概览和未来研究方向。
Sleep and epilepsy: A snapshot of knowledge and future research lines.
机构信息
Child Neuropsychiatric Unit, Istituto G. Gaslini, Genoa, Italy.
Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DiNOGMI), University of Genoa, Genoa, Italy.
出版信息
J Sleep Res. 2022 Aug;31(4):e13622. doi: 10.1111/jsr.13622. Epub 2022 Apr 29.
Abstract
Sleep and epilepsy have a reciprocal relationship, and have been recognized as bedfellows since antiquity. However, research on this topic has made a big step forward only in recent years. In this narrative review we summarize the most stimulating discoveries and insights reached by the "European school." In particular, different aspects concerning the sleep-epilepsy interactions are analysed: (a) the effects of sleep on epilepsy; (b) the effects of epilepsy on sleep structure; (c) the relationship between epilepsy, sleep and epileptogenesis; (d) the impact of epileptic activity during sleep on cognition; (e) the relationship between epilepsy and the circadian rhythm; (f) the history and features of sleep hypermotor epilepsy and its differential diagnosis; (g) the relationship between epilepsy and sleep disorders.
摘要
睡眠与癫痫之间存在相互关系，自古以来就被认为是“难兄难弟”。然而，近年来，这一课题的研究才取得了重大进展。在本篇综述中，我们总结了“欧洲学派”最具启发性的发现和见解。具体而言，我们分析了睡眠-癫痫相互作用的不同方面：(a)睡眠对癫痫的影响；(b)癫痫对睡眠结构的影响；(c)癫痫、睡眠与癫痫发生的关系；(d)睡眠期间癫痫活动对认知的影响；(e)癫痫与昼夜节律的关系；(f)睡眠运动性癫痫的历史、特征及其鉴别诊断；(g)癫痫与睡眠障碍的关系。
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