Department of Microbiology, School of Basic Medicine, Zunyi Medical University, Zunyi, Guizhou, China.
Livestock and Poultry Biological Products Key Laboratory of Sichuan Province, Sichuan Animal Science Academy, Chengdu, China.
J Med Virol. 2023 Jul;95(7):e28924. doi: 10.1002/jmv.28924.
Since the onset of the pandemic caused by severe acute respiratory syndrome coronavirus 2, messenger RNA (mRNA) vaccines have demonstrated outstanding performance. mRNA vaccines offer significant advantages over conventional vaccines in production speed and cost-effectiveness, making them an attractive option against other viral diseases. This article reviewed recent advances in viral mRNA vaccines and their delivery systems to provide references and guidance for developing mRNA vaccines for new viral diseases.
自严重急性呼吸综合征冠状病毒 2 引起的大流行以来，信使 RNA（mRNA）疫苗已经表现出了卓越的性能。mRNA 疫苗在生产速度和成本效益方面优于传统疫苗，因此成为对抗其他病毒性疾病的一种有吸引力的选择。本文综述了病毒 mRNA 疫苗及其传递系统的最新进展，为开发针对新病毒性疾病的 mRNA 疫苗提供了参考和指导。
