University of Minnesota College of Pharmacy, Department of Pharmacy Practice and Pharmaceutical Sciences, Duluth, Minnesota.
Human Development Center, Department of Psychiatry, Duluth, Minnesota.
Prim Care Companion CNS Disord. 2023 Jun 27;25(3):22m03432. doi: 10.4088/PCC.22m03432.
To evaluate the effectiveness of a quality improvement (QI) initiative to improve family medicine residents' metabolic monitoring of second-generation antipsychotics (SGAs) for patients comanaged across nonintegrated community mental health and family medicine clinics. Patients were aged ≥ 18 years seen by family medicine residents and prescribed at least 1 SGA (N = 175). Preparative and scheduled QI interventions were nonblinded and included collaboration across organizations, education, and monthly interprofessional care conferences. The QI outcome included evaluation of pre-post metabolic monitoring laboratory data over the 15-month study period. A subset of patients (n = 26) was reviewed at least once at monthly interprofessional care conferences. Patients were stratified by diagnosis of diabetes (n = 45) and no diabetes (n = 130) at baseline. Analyses of the QI intervention outcomes were framed by the time period of monthly care conferences (January 31, 2019-April 30, 2020) and compared to baseline (the historical time period) (October 31, 2017-January 29, 2019). Improved adherence in glycated hemoglobin (HbA) ( = .042) and lipid ( < .001) monitoring per guidelines from baseline to follow-up was seen in the total patient population (N = 175). Patients without diabetes (n = 130) had significant improvement ( = .001) in HbA monitoring from baseline to follow-up. The subgroup of patient cases that were discussed at a care conference showed no significant improvement in HbA or lipid monitoring. Preparative and scheduled QI interventions provided family medicine residents powerful reminders of the SGA monitoring guidelines that improved the metabolic monitoring behaviors for all patients on SGAs. .
为了评估一项质量改进(QI)计划的有效性,该计划旨在改善家庭医学住院医师对共管理的非综合社区心理健康和家庭医学诊所患者的第二代抗精神病药物(SGAs)的代谢监测。患者年龄≥18 岁,由家庭医学住院医师就诊,并至少开具一种 SGA(N=175)。预备和计划的 QI 干预是非盲的,包括跨组织合作、教育和每月的跨专业护理会议。QI 结果包括在 15 个月的研究期间评估代谢监测实验室数据的前后变化。在每月的跨专业护理会议上,对至少一部分患者(n=26)进行了回顾。患者在基线时按糖尿病诊断(n=45)和无糖尿病(n=130)分层。QI 干预结果的分析以每月护理会议的时间段为框架(2019 年 1 月 31 日至 2020 年 4 月 30 日),并与基线(历史时间段)(2017 年 10 月 31 日至 2019 年 1 月 29 日)进行比较。在总患者人群(N=175)中,HbA( = .042)和脂质( < .001)监测的依从性按照指南从基线到随访有所改善。无糖尿病的患者(n=130)HbA 监测从基线到随访有显著改善( = .001)。在护理会议上讨论的患者病例亚组在 HbA 或脂质监测方面没有显著改善。预备和计划的 QI 干预为家庭医学住院医师提供了强有力的第二代抗精神病药物监测指南提示,改善了所有 SGA 患者的代谢监测行为。