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促黄体生成素释放激素的放射免疫测定。标准曲线与特异性。

Radioimmunoassay of LH-RH. Standard curves and specificity.

作者信息

Teuwissen B, Fauconnier J P, Thomas K

出版信息

Gynecol Invest. 1978;9(4):170-82. doi: 10.1159/000300982.

DOI:10.1159/000300982
PMID:374203
Abstract

As important discrepancies in blood concentrations of LH-RH remain, the basic problem of the specificity of the radioimmunoassay was reinvestigated using an antiserum raised against a new conjugate (33). Cross-reactions with related and unrelated peptides were studied in both charcoal-dextran and second antibody methods of separation. The possible relation between the nature of the conjugate and the specificity is discussed.

摘要

由于促黄体生成激素释放激素(LH-RH)血药浓度仍存在重要差异,因此使用针对一种新偶联物制备的抗血清,对放射免疫分析特异性的基本问题进行了重新研究(33)。在炭-葡聚糖和第二抗体分离法中,研究了与相关和不相关肽的交叉反应。讨论了偶联物性质与特异性之间的可能关系。

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Radioimmunoassay of LH-RH. Standard curves and specificity.促黄体生成素释放激素的放射免疫测定。标准曲线与特异性。
Gynecol Invest. 1978;9(4):170-82. doi: 10.1159/000300982.
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[Studies on the measurements of LH-releasing hormone (LH-RH) by radioimmunoassay (RIA) (author's transl)].放射免疫分析法测定促黄体生成激素释放激素(LH-RH)的研究(作者译)
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