Strassman A, Mason P, Moskowitz M, Maciewicz R
Brain Res. 1986 Aug 6;379(2):242-50. doi: 10.1016/0006-8993(86)90777-8.
The extracellular response of medullary trigeminal neurons to electrical stimulation of the dura was studied in anesthetized cats. Fifty-six medullary trigeminal units were excited by stimulation sites near major dural vessels with an average latency of 11.0 ms. Many units also responded to infraorbital nerve shock and had cutaneous receptive fields that included the ipsilateral periorbital region. These cutaneous responses were either wide dynamic range or nociceptive specific in type. Electrical stimulation of the midbrain periaqueductal gray region suppressed the response of medullary trigeminal units to either dural stimulation or infraorbital nerve shock. Medullary trigeminal neurons that receive convergent inputs from dura and facial skin may provide a physiological substrate for the cutaneous referral of dural sensation.
在麻醉猫身上研究了延髓三叉神经神经元对硬脑膜电刺激的细胞外反应。56个延髓三叉神经单位被主要硬脑膜血管附近的刺激部位兴奋，平均潜伏期为11.0毫秒。许多单位也对眶下神经冲击有反应，并且有包括同侧眶周区域的皮肤感受野。这些皮肤反应类型为宽动态范围或伤害性特异性。中脑导水管周围灰质区域的电刺激抑制了延髓三叉神经单位对硬脑膜刺激或眶下神经冲击的反应。从硬脑膜和面部皮肤接受汇聚输入的延髓三叉神经神经元可能为硬脑膜感觉的皮肤牵涉提供生理基础。
