可穿戴声学传感器在诊断应用中的研究进展。

Progress in wearable acoustical sensors for diagnostic applications.

机构信息

Key Laboratory of Microsystems and Microstructures Manufacturing, Ministry of Education, Harbin Institute of Technology, Harbin, 150080, China.

Functional Materials and Acousto-optic Instruments Institute, School of Instrumentation Science and Engineering, Harbin Institute of Technology, Harbin, 150080, China.

出版信息

Biosens Bioelectron. 2023 Oct 1;237:115509. doi: 10.1016/j.bios.2023.115509. Epub 2023 Jul 5.

DOI:10.1016/j.bios.2023.115509

PMID:37423066

Abstract

With extensive and widespread uses of miniaturized and intelligent wearable devices, continuously monitoring subtle spatial and temporal changes in human physiological states becomes crucial for daily healthcare and professional medical diagnosis. Wearable acoustical sensors and related monitoring systems can be comfortably applied onto human body with a distinctive function of non-invasive detection. This paper reviews recent advances in wearable acoustical sensors for medical applications. Structural designs and characteristics of the structural components of wearable electronics, including piezoelectric and capacitive micromachined ultrasonic transducer (i.e., pMUT and cMUT), surface acoustic wave sensors (SAW) and triboelectric nanogenerators (TENGs) are discussed, along with their fabrication techniques and manufacturing processes. Diagnostic applications of these wearable sensors for detection of biomarkers or bioreceptors and diagnostic imaging have further been discussed. Finally, main challenges and future research directions in these fields are highlighted.

摘要

随着微型化和智能化可穿戴设备的广泛应用，持续监测人体生理状态的细微时空变化对于日常医疗保健和专业医疗诊断变得至关重要。可穿戴声学传感器和相关监测系统可以舒适地应用于人体，具有独特的非侵入性检测功能。本文综述了用于医疗应用的可穿戴声学传感器的最新进展。讨论了可穿戴电子产品的结构设计和结构组件的特性，包括压电和电容式微机械超声换能器（即 pMUT 和 cMUT）、声表面波传感器（SAW）和摩擦电纳米发电机（TENG），以及它们的制造技术和制造工艺。进一步讨论了这些可穿戴传感器在生物标志物或生物感受器检测和诊断成像方面的诊断应用。最后，强调了这些领域的主要挑战和未来研究方向。