Division of Trauma Surgery, Department of Surgery, Ajou University School of Medicine, 164 World Cup-ro, Yeongtong-gu, Suwon, 16499, Republic of Korea.
Department of Thoracic and Cardiovascular Surgery, Ajou University School of Medicine, Suwon, Republic of Korea.
World J Surg. 2023 Oct;47(10):2347-2355. doi: 10.1007/s00268-023-07110-5. Epub 2023 Jul 9.
Traumatic inferior vena cava (IVC) injuries are uncommon, but the mortality rate remains high at 38-70%. To date, most studies on traumatic IVC injuries have evaluated blunt rather than penetrating injuries. We aimed to identify the clinical features and risk factors that affect the prognosis of patients with blunt IVC injuries to improve treatment strategies for these patients.
We retrospectively analyzed patients diagnosed with blunt IVC injury over 8 years at a single trauma center. Clinical and biochemical parameters; transfusion, surgical, and resuscitation methods; associated injuries; intensive care unit stay; and complications data were compared between survival and death groups to identify clinical features and risk factors of blunt IVC injury-related mortality.
Twenty-eight patients with blunt IVC injury were included during the study periods. Twenty-five (89%) patients underwent surgical treatment, and the mortality was 54%. The mortality rate according to the IVC injury location was the lowest for supra-hepatic IVC injury (25%, n = 2/8), whereas it was the highest for retrohepatic IVC injury (80%, n = 4/5). In the logistic regression analysis, Glasgow Coma Scale (GCS) (odds ratio [OR] = 0.566, 95% confidence interval [CI] [0.322-0.993], p = 0.047) and red blood cell (RBC) transfusion for 24 h (OR = 1.132, 95% CI [0.996-1.287], p = 0.058) were independent predictors for mortality.
Low GCS score and high-volume packed RBC transfusion requirements for 24 h were significant predictors of mortality in patients with blunt IVC injuries. Unlike IVC injuries caused by penetrating trauma, supra-hepatic IVC injuries caused by blunt trauma have a good prognosis.
创伤性下腔静脉(IVC)损伤并不常见,但死亡率仍高达 38-70%。迄今为止,大多数关于创伤性 IVC 损伤的研究都评估了钝性而非穿透性损伤。我们旨在确定影响钝性 IVC 损伤患者预后的临床特征和危险因素,以改善这些患者的治疗策略。
我们回顾性分析了在一家创伤中心 8 年期间诊断为钝性 IVC 损伤的患者。比较了存活组和死亡组之间的临床和生化参数;输血、手术和复苏方法;合并伤;重症监护病房停留时间和并发症数据,以确定钝性 IVC 损伤相关死亡率的临床特征和危险因素。
研究期间共纳入 28 例钝性 IVC 损伤患者。25 例(89%)患者接受了手术治疗,死亡率为 54%。根据 IVC 损伤部位,肝上 IVC 损伤的死亡率最低(25%,n=2/8),而肝后 IVC 损伤的死亡率最高(80%,n=4/5)。在逻辑回归分析中,格拉斯哥昏迷量表(GCS)(比值比[OR] = 0.566,95%置信区间[CI] [0.322-0.993],p=0.047)和 24 小时红细胞(RBC)输注量(OR = 1.132,95% CI [0.996-1.287],p=0.058)是死亡率的独立预测因素。
低 GCS 评分和 24 小时内大量 RBC 输血需求是钝性 IVC 损伤患者死亡的显著预测因素。与穿透性创伤引起的 IVC 损伤不同,钝性创伤引起的肝上 IVC 损伤预后良好。