Padmavathi Arumugam, Vijayaraghavan Ramasamy, Prakash Balu
Department of Microbiology, Nehru Arts & Science College Coimbatore, TN, India.
Department of Microbiology, PSG College of Arts and Science, Coimbatore, TN, India.
Bioinformation. 2022 Sep 30;18(9):780-785. doi: 10.6026/97320630018780. eCollection 2022.
Sixteen keratinolytic bacteria were isolated from poultry farm soil samples. The highest keratinlytic enzyme producers of Bacillus flexus was confirmed with 16S rRNA sequence analysis. It is of interest to understand the binding efficiency of the modelled keratinase from Bacillus flexus with different substrates using molecular docking studies. Data provides insights for the identification of substrate recognition patterns, and the development of suitable enzymes to improve their use in keratin degradation.
从家禽养殖场土壤样本中分离出16株角蛋白分解细菌。通过16S rRNA序列分析证实了弯曲芽孢杆菌是最高产角蛋白分解酶的菌株。利用分子对接研究来了解弯曲芽孢杆菌模拟角蛋白酶与不同底物的结合效率是很有意义的。这些数据为识别底物识别模式以及开发合适的酶以提高其在角蛋白降解中的应用提供了见解。