Corson J D, Chang B B, Leopold P W, DeLeo B, Shah D M, Leather R P, Karmody A M
Circulation. 1986 Sep;74(3 Pt 2):I1-4.
Two alternative anesthetic techniques for use during carotid endarterectomy were studied in a series of 424 procedures. A total of 248 were performed in patients under general anesthesia and 176 patients received regional block anesthesia. Perioperative instability of blood pressure was noted in 108 patients. Hypertension was noted in 17.7% of those under general anesthesia vs 20.5% of those under regional block anesthesia. Intravenous vasodilator agents were used for 19.62 hr (+/- 4.33) in the general anesthesia group vs 1.4 hr (+/- 0.44) in the regional block anesthesia group (p less than .02). Perioperative hypertension correlated best with uncontrolled preoperative hypertension. Under regional block anesthesia the incidence of shunting was 4.5%. The 1 month operative mortality for the entire carotid series was 1.2% (5/424). There were three stroke-related deaths. In addition, two nonfatal major strokes and two minor strokes occurred in patients who received general anesthesia vs one nonfatal major stroke in a patient who received regional block anesthesia.
在一系列424例颈动脉内膜切除术过程中,对两种可供选择的麻醉技术进行了研究。共有248例手术在全身麻醉下进行,176例患者接受区域阻滞麻醉。108例患者出现围手术期血压不稳定。全身麻醉患者中高血压发生率为17.7%,区域阻滞麻醉患者中为20.5%。全身麻醉组静脉使用血管扩张剂的时间为19.62小时(±4.33),区域阻滞麻醉组为1.4小时(±0.44)(p<0.02)。围手术期高血压与术前未控制的高血压相关性最强。在区域阻滞麻醉下,分流发生率为4.5%。整个颈动脉手术系列的1个月手术死亡率为1.2%(5/424)。有3例与中风相关的死亡。此外,接受全身麻醉的患者发生了2例非致命性大中风和2例小中风,而接受区域阻滞麻醉的患者发生了1例非致命性大中风。