Andersen C A, Rich N M, Collins G J, McDonald P T
Am Surg. 1980 Jun;46(6):323-7.
The records of 421 patients who underwent carotid endarterectomy were reviewed. Between 1967 and 1972 carotid endarterectomy was performed with regional anesthesia in 232 patients. Ten per cent of these patients required the use of general anesthesia and a temporary indwelling shunt, because of the development of neurologic symptoms after temporary cross-clamping (5.6%) or the inability to tolerate regional anesthesia (4.3%). The 30-day mortality was 2.6 per cent. The incidence of fixed neurologic deficits was 2.2 per cent, and the incidence of transient neurologic deficits was 3 per cent. Between 1974 and 1976, 189 carotid endarterectomies were performed with general anesthesia and the routine use of a temporary indwelling shunt. The 30-day mortality was 0.5 per cent. The incidence of fixed neurologic deficits was 2.6 per cent; the incidence of transient neurologic deficits was 2.6 per cent. The use of general anesthesia with a shunt has not significantly changed the mortality or incidence of postoperative neurologic complications when compared with the authors' series performed with regional anesthesia. All patients in whom postoperative strokes occurred had multiple stenotic or occlusive lesions. Special precautions should be taken in this high-risk group.
对421例行颈动脉内膜切除术患者的记录进行了回顾。1967年至1972年间,232例患者在区域麻醉下进行了颈动脉内膜切除术。这些患者中有10%因临时夹闭后出现神经症状(5.6%)或无法耐受区域麻醉(4.3%)而需要使用全身麻醉和临时留置分流管。30天死亡率为2.6%。永久性神经功能缺损的发生率为2.2%,短暂性神经功能缺损的发生率为3%。1974年至1976年间,189例颈动脉内膜切除术在全身麻醉和常规使用临时留置分流管的情况下进行。30天死亡率为0.5%。永久性神经功能缺损的发生率为2.6%;短暂性神经功能缺损的发生率为2.6%。与作者采用区域麻醉进行的系列手术相比,使用全身麻醉并分流管并未显著改变死亡率或术后神经并发症的发生率。所有发生术后中风的患者均有多处狭窄或闭塞性病变。对此高危组应采取特殊预防措施。