供体人工授精（AID）的基因筛查。对676名精液供体的研究结果。

Genetic screening for artificial insemination by donor (AID). Results of a study on 676 semen donors.

作者信息

Selva J, Leonard C, Albert M, Auger J, David G

出版信息

Clin Genet. 1986 May;29(5):389-96. doi: 10.1111/j.1399-0004.1986.tb00510.x.

DOI:10.1111/j.1399-0004.1986.tb00510.x

Abstract

We report the results of our ten-year experience in the Centre for Study and Conservation of Human Semen (CECOS) in Paris-Bicêtre. A total of 676 potential semen donors were interviewed by a geneticist and karyotyped; 6.0% were excluded, i.e. 2.6% for a cytogenetic reason and 3.4% for a genic reason. Our experience stresses the subjectivity and difficulty of the exclusion decision. It also shows how useful it is to take into account the recipient's familial pathology when choosing the donor. Finally, it reveals the importance of the geneticist's participation in the functioning of a centre.

摘要

我们报告了我们在巴黎比塞特人类精液研究与保存中心（CECOS）十年的经验结果。共有676名潜在精液捐赠者接受了遗传学家的访谈并进行了核型分析；6.0%被排除，即2.6%是由于细胞遗传学原因，3.4%是由于基因原因。我们的经验强调了排除决定的主观性和困难性。它还表明在选择捐赠者时考虑受者家族病理情况是多么有用。最后，它揭示了遗传学家参与中心运作的重要性。