前瞻性出生队列研究中选择偏倚的重要性。
The importance of selection bias in prospective birth cohort studies.
作者信息
Larsson Henrik
机构信息
School of Medical Sciences Örebro University Örebro Sweden.
Department of Medical Epidemiology and Biostatistics Karolinska Institutet Stockholm Sweden.
出版信息
JCPP Adv. 2021 Nov 10;1(3):e12043. doi: 10.1002/jcv2.12043. eCollection 2021 Oct.
Abstract
Sophisticated statistical analyses of data from large-scale prospective birth cohort studies combined with thoughtful study designs have advanced understanding about the causes, consequences and developmental course of child and adolescent mental health problems. Available large-scale prospective cohort studies, such as ALSPAC, MoBA, and TEDS have many noteworthy strengths, but they all suffer from non-random non-participation and attrition over time. Recent findings have highlighted that prospective birth cohort studies need to carefully consider the importance of selection bias.
摘要
对来自大规模前瞻性出生队列研究的数据进行复杂的统计分析，并结合周到的研究设计，加深了人们对儿童和青少年心理健康问题的成因、后果及发展过程的理解。现有的大规模前瞻性队列研究，如阿冯纵向父母与儿童研究（ALSPAC）、挪威母亲与儿童队列研究（MoBA）和双生子早期发展研究（TEDS），有许多值得注意的优点，但它们都存在非随机不参与和随时间推移的损耗问题。最近的研究结果强调，前瞻性出生队列研究需要仔细考虑选择偏倚的重要性。
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