Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China.
Key Laboratory of Bioactive Substances and Resource Utilization of Chinese Herbal Medicine, Ministry of Education, Beijing 100193, China.
Nutrients. 2023 May 8;15(9):2233. doi: 10.3390/nu15092233.
is a common functional vegetable with edible and medicinal value. plants have a special spicy taste, so they are often used as food and seasoning in people's diets. As a functional food, also has abundant biological activities, some of which are used as drugs to treat diseases. By consuming on a daily basis, people can receive active compounds of natural origin, thereby improving their health status and reducing the likelihood of disease. Steroidal saponins are important secondary metabolites of , which are formed by the steroidal aglycone group and sugar. Steroidal saponins have various physiological activities, such as hypoglycemic, antiplatelet aggregation, anti-inflammatory, antitumor, antimicrobial, and enzyme activity inhibition, which is one of the key reasons why has such significant health benefits. The structural diversity and rich biological activities of steroidal saponins make important plants for both food and medicine. In this paper, the chemical structures, biological activities, and structure-activity relationships of steroidal saponins isolated from are reviewed, and the biosynthetic pathways of some key compounds are proposed as well, to provide a molecular reference basis based on secondary metabolites for the health value of .
是一种常见的功能性蔬菜,具有食用和药用价值。 植物具有特殊的辛辣味,因此在人们的饮食中常被用作食物和调味料。作为一种功能性食品, 也具有丰富的生物活性,其中一些被用作药物来治疗疾病。通过每天食用 ,人们可以获得天然来源的活性化合物,从而改善健康状况,降低患病的可能性。甾体皂苷是 的重要次生代谢产物,由甾体苷元基团和糖组成。甾体皂苷具有多种生理活性,如降血糖、抗血小板聚集、抗炎、抗肿瘤、抗菌和抑制酶活性等,这也是 具有如此显著健康益处的关键原因之一。甾体皂苷的结构多样性和丰富的生物活性使 成为兼具食品和药用价值的重要植物。本文综述了 中分离得到的甾体皂苷的化学结构、生物活性和构效关系,并提出了一些关键化合物的生物合成途径,为 提供了基于次生代谢物的健康价值的分子参考依据。