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血清和尿道抗体反应在生殖支原体感染男性。

Serum and Urethral Antibody Response in Mycoplasma genitalium -Infected Men.

机构信息

From the Division of Allergy and Infectious Diseases, Department of Medicine.

Center for AIDS and STD and Department of Epidemiology, University of Washington, Seattle, WA.

出版信息

Sex Transm Dis. 2023 Oct 1;50(10):e26-e29. doi: 10.1097/OLQ.0000000000001845. Epub 2023 Jul 2.

DOI:10.1097/OLQ.0000000000001845
PMID:37432986
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10527067/
Abstract

The antibody response to Mycoplasma genitalium in serum and urethral secretions of men with nongonococcal urethritis was examined longitudinally. Serum and urethral antibodies reacted primarily with the MgpB and MgpC adhesins. Serum antibodies persisted throughout follow-up, whereas urethral antibodies waned despite organism persistence. Declining antibodies may facilitate chronic infection.

摘要

本研究对非淋球菌性尿道炎患者血清和尿道分泌物中的支原体属生殖器抗体应答进行了纵向研究。血清和尿道抗体主要与 MgpB 和 MgpC 黏附素反应。尽管存在病原体，但血清抗体在随访期间持续存在，而尿道抗体却逐渐减少。抗体的下降可能促进了慢性感染。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/68fd/10527067/ff6b70150811/nihms-1913331-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/68fd/10527067/0a67a840766c/nihms-1913331-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/68fd/10527067/275a667ff4aa/nihms-1913331-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/68fd/10527067/ff6b70150811/nihms-1913331-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/68fd/10527067/0a67a840766c/nihms-1913331-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/68fd/10527067/275a667ff4aa/nihms-1913331-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/68fd/10527067/ff6b70150811/nihms-1913331-f0003.jpg

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