Di Falco G, Guccione C, D'Annibale A, Ronsisvalle S, Lavezzo P, Fregonese D, D'Ambrosio G
Dis Colon Rectum. 1986 Sep;29(9):582-5. doi: 10.1007/BF02554263.
Fournier's disease is an uncommon form of gas gangrene involving the scrotum and perineum. Described by Fournier as an idiopathic condition, it must be recognized as a synergistic gangrene secondary, in most cases, to a focus of perianal infection. Urinary tract infection and local trauma follow as possible causal factors. Five cases complicating a perianal abscess observed in a period of 11 years have been treated with urgent aggressive surgical debridement and intensive care support. Full-thickness skin grafts were required in three patients. Hospital mortality occurred in one case. Although combination antibiotic therapy and correct postoperative wound management are potentially successful, the mainstay of treatment is complete excision of all necrotic tissue. Colostomy and urinary diversion are not mandatory. Treatment with hyperbaric oxygen is controversial.
福尼尔坏疽是一种累及阴囊和会阴的罕见气性坏疽形式。福尼尔将其描述为一种特发性疾病，但在大多数情况下，必须认识到它是继发于肛周感染灶的协同性坏疽。尿路感染和局部创伤也可能是致病因素。在11年期间观察到5例肛周脓肿并发福尼尔坏疽的病例，均接受了紧急积极的手术清创和重症监护支持。3例患者需要进行全层皮肤移植。1例发生医院死亡。虽然联合抗生素治疗和正确的术后伤口处理可能成功，但治疗的关键是彻底切除所有坏死组织。结肠造口术和尿路改道并非必需。高压氧治疗存在争议。
