Department of Health Services Research, Management and Policy, College of Public Health and Health Professions, University of Florida, Gainesville, Florida, USA.
Department of Family and Community Health Sciences, College of Nursing, University of Florida, Gainesville, Florida, USA.
J Integr Complement Med. 2023 Nov;29(11):757-766. doi: 10.1089/jicm.2023.0020. Epub 2023 Jul 11.
Fibromyalgia syndrome (FMS) is characterized by widespread persistent musculoskeletal pain. Mostly prevalent among White women, little is known about FMS in other population cohorts. This study examined secondary data of a racially diverse sample of women with FMS that were collected as part of a randomized controlled clinical trial that examined the effect of a complementary therapy intervention over the course of a 10-week guided imagery intervention to identify demographic, social, or economic differences in self-reported pain. The Brief Pain Inventory (BPI), which measures pain severity and interference, was administered to 72 women (21 Black and 51 Whites) at baseline, 6 and 10 weeks. Student's tests and time series regression models examined racial difference in pain dimensions and treatment response. Regression models accounted for age, race, income, duration of symptoms, treatment group, pain at baseline, smoking, alcohol use, comorbid conditions, and time. Black women experienced significantly higher pain severity ( = 5.52, standard deviation [SD] = 2.13) and interference ( = 5.54, SD = 2.74) than Whites (severity = 4.56, SD = 2.08; interference = 4.72, SD = 2.76) (interference: = 1.92, = 0.05; severity: = 2.95, = 0.00). Disparities persisted over time. Controlling for differences in age, income, and previous pain levels, Black women had 0.26 (standard error [SE] = 0.065) higher pain severity and 0.36 (SE = 0.078) higher interference than Whites. Low-income earners also experienced 2.02 (SE = 0.38) and 2.19 (SE = 0.46) higher pain severity and interference, respectively, than other earners. Results were robust to inclusion of comorbidities. Black women and low-income earners experienced significantly higher levels of pain severity and interference and a lower dose response to the intervention. Differentials were robust to inclusion of demographic, health, and behavioral characteristics. Findings suggest that external factors may contribute to pain perception among women with FMS.
纤维肌痛综合征(FMS)的特征是广泛持续的肌肉骨骼疼痛。FMS 在白种女性中更为常见,但在其他人群队列中对其了解甚少。本研究利用一项随机对照临床试验的二次数据,该试验检查了补充疗法干预对为期 10 周的引导想象干预过程中纤维肌痛综合征女性自我报告疼痛的影响,以此来检验种族差异。在基线、6 周和 10 周时,对 72 名女性(21 名黑人,51 名白人)进行了简明疼痛量表(BPI)评估,该量表用于测量疼痛严重程度和干扰程度。学生检验和时间序列回归模型检验了疼痛维度和治疗反应的种族差异。回归模型考虑了年龄、种族、收入、症状持续时间、治疗组、基线疼痛、吸烟、饮酒、合并症和时间。黑人女性的疼痛严重程度( = 5.52,标准差 [SD] = 2.13)和干扰( = 5.54,SD = 2.74)明显高于白人(严重程度 = 4.56,SD = 2.08;干扰 = 4.72,SD = 2.76)(干扰: = 1.92, = 0.05;严重程度: = 2.95, = 0.00)。差异持续存在。在控制年龄、收入和以前疼痛水平的差异后,黑人女性的疼痛严重程度比白人高 0.26(标准误差 [SE] = 0.065),干扰程度高 0.36(SE = 0.078)。与其他收入者相比,低收入者的疼痛严重程度和干扰程度也分别高出 2.02(SE = 0.38)和 2.19(SE = 0.46)。结果在纳入合并症后仍然稳健。黑人女性和低收入者经历了更高水平的疼痛严重程度和干扰,对干预的反应较低。差异在纳入人口统计学、健康和行为特征后仍然稳健。这些发现表明,外部因素可能会导致患有纤维肌痛综合征的女性产生疼痛感知。