Rym Maamouri, Wijden Nabi, Héla Maamouri, Héla Sassi, Nozha Brahmi, Cheour Monia
Department of Ophthalmology, Habib Thameur hospital, Tunis, Tunisia.
Faculty of Medicine of Tunis, University of Tunis El Manar, Tunis, Tunisia.
Neuroophthalmology. 2023 May 11;47(4):193-198. doi: 10.1080/01658107.2023.2205926. eCollection 2023.
Acute methanol poisoning is first and foremost life-threatening. Otherwise, functional prognosis is mainly based on ocular impairment. In this case series we aimed to describe the ocular manifestations after acute methanol poisoning during an outbreak in Tunisia. The data from 21 patients (41 eyes) were analysed. All patients underwent a complete ophthalmological examination including visual fields, colour vision test and optical coherence tomography with evaluation of the retinal nerve fibre layer. Patients were classified into two groups. Group 1 included patients with visual symptoms and group 2 included patients with no visual symptoms. Ocular abnormalities were seen in 81.8% of patients with ocular symptoms. They included: optic neuropathy in 7 patients (63.6%); central retinal artery occlusion in 1 patient (9.1%); and central serous chorioretinopathy in 1 patient (9.1%). Mean blood methanol levels were significantly higher in patients without ocular symptoms ( = .03).
急性甲醇中毒首先会危及生命。否则,功能预后主要基于眼部损伤情况。在本病例系列中,我们旨在描述突尼斯一次疫情期间急性甲醇中毒后的眼部表现。分析了21例患者(41只眼)的数据。所有患者均接受了全面的眼科检查,包括视野检查、色觉测试和光学相干断层扫描,并对视网膜神经纤维层进行了评估。患者被分为两组。第1组包括有视觉症状的患者,第2组包括无视觉症状的患者。有眼部症状的患者中81.8%出现了眼部异常。其中包括:7例(63.6%)视神经病变;1例(9.1%)视网膜中央动脉阻塞;1例(9.1%)中心性浆液性脉络膜视网膜病变。无眼部症状患者的平均血液甲醇水平显著更高(P = 0.03)。