Emergency Medicine Research Center, Shiraz University of Medical Sciences, Shiraz, Iran; Emergency Medicine Department, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Student Research Committee, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Am J Emerg Med. 2022 Feb;52:69-84. doi: 10.1016/j.ajem.2021.11.026. Epub 2021 Nov 24.
In this systematic scoping review, it was aimed to assess the epidemiology of methanol poisoning, clinical findings and patients' management, causes, and recommendations regarding prevention or reduction of methanol poisoning during COVID-19 pandemic.
Three Electronic databases [Medline (accessed from PubMed), Scopus, and Science Direct] were searched systematically from December 01, 2019 to September 10, 2020, using MESH terms and the related keywords in English language. Considering the titles and abstracts, unrelated studies were excluded. The full texts of the remained studies were evaluated by authors, independently. Then, the studies' findings were assessed and reported.
Total of 86 articles were obtained within the first step of searching, and 64 ones remained after removing the duplications. Through the title and abstract screening, 35 were removed. Finally, after reading the full text of the remained articles, 15 ones included in data extraction. Most of the previous reported evidence (13/15) were letter to editor, commentary and short reports. None of them were interventional, and none of them followed the patients. Findings were summarized in four categories: 1) epidemiology; 2) clinical findings and patients' management; 3) causes; and 4) recommendation regarding prevention or reduction of methanol poisoning during COVID-19 pandemic.
The recent outbreak is the largest methanol mass poisoning outbreak throughout Iran and the world in recent decades. The causes of methanol poisoning during the COVID-19 pandemic are intertwined, and most of them are modifiable by health policy makers. Building trust, educating and warning, as well as controlling and monitoring are three main recommendation for prevention or reduction of methanol poisoning.
在本次系统范围的综述中，旨在评估甲醇中毒的流行病学、临床发现和患者管理、中毒原因以及关于在 COVID-19 大流行期间预防或减少甲醇中毒的建议。
从 2019 年 12 月 1 日至 2020 年 9 月 10 日，使用 Medline（从 PubMed 访问）、Scopus 和 Science Direct 这三个电子数据库，以英文的 MESH 术语和相关关键词进行系统搜索。根据标题和摘要，排除不相关的研究。作者独立评估并报告了剩余研究的全文。然后，评估并报告了研究结果。
在第一步搜索中总共获得了 86 篇文章，去除重复后保留了 64 篇。通过标题和摘要筛选，排除了 35 篇。最后，在阅读了其余文章的全文后，有 15 篇文章纳入数据提取。之前报道的大多数证据（13/15）都是给编辑的信、评论和短篇报告。没有一个是干预性的，也没有一个是跟踪患者的。研究结果总结为四个类别：1）流行病学；2）临床发现和患者管理；3）中毒原因；4）关于在 COVID-19 大流行期间预防或减少甲醇中毒的建议。
最近的爆发是伊朗和世界近几十年来最大的甲醇大规模中毒爆发。COVID-19 大流行期间甲醇中毒的原因相互交织，其中大多数原因可通过卫生政策制定者进行改变。建立信任、教育和警告以及控制和监测是预防或减少甲醇中毒的三个主要建议。
