Ghosh Ritwik, León-Ruiz Moisés, Sardar Sona Singh, Lalsing D Padavi, Benito-León Julián
Department of General Medicine, Burdwan Medical College and Hospital, Burdwan, India.
Section of Clinical Neurophysiology, Department of Neurology, University Hospital "La Paz", Madrid, Spain.
Neuroophthalmology. 2023 Mar 13;47(4):218-224. doi: 10.1080/01658107.2023.2186431. eCollection 2023.
Listeria monocytogenes has tropism towards two immunologically "privileged" sites, the fetoplacental unit in pregnant women and the central nervous system (neurolisteriosis) in immunocompromised individuals. We report a case of neurolisteriosis in a previously asymptomatic pregnant woman from rural West Bengal, India, who presented with a subacute onset febrile illness with features of rhombencephalitis and a predominantly midline-cerebellopathy (slow and dysmetric saccades, florid downbeat nystagmus, horizontal nystagmus, and ataxia). With timely detection and the institution of prolonged intravenous antibiotic therapy, both the mother and the fetus were saved uneventfully.
单核细胞增生李斯特菌倾向于定位于两个免疫“特权”部位，即孕妇的胎盘胎儿单位以及免疫功能低下个体的中枢神经系统（神经李斯特菌病）。我们报告了一例来自印度西孟加拉邦农村的既往无症状孕妇发生神经李斯特菌病的病例，该孕妇以亚急性发热性疾病起病，伴有菱形脑炎特征及以中线小脑病变为主（缓慢且不对称性眼球震颤、明显的下跳性眼球震颤、水平性眼球震颤和共济失调）。通过及时检测并给予长时间静脉抗生素治疗，母亲和胎儿均顺利获救。
