Wang Peng, Pang Xin, He Mingxuan, Liu Jinyan
Department of Internal Medicine-Oncology, The Second Hospital of Baoding Baoding 071051, Hebei, China.
Department of General Practice, The Affiliated Hospital of Hebei University (North House) Baoding 071000, Hebei, China.
Am J Transl Res. 2023 Jun 15;15(6):4055-4064. eCollection 2023.
To explore the effect of stepwise psychological intervention on adverse mood and quality of life of patients after colon cancer surgery.
The clinical data from 102 patients with colon cancer admitted to the Second Hospital of Baoding from January 2018 to June 2022 were collected and analyzed retrospectively. Based on the intervention measures, 51 patients with the general intervention were regarded as the general group, and 51 patients with the stepwise psychological intervention were considered as the intervention group. Piper Fatigue Scale (PFS) was used to scale the degree of Cancer-related fatigue (CRF); Self-rating anxiety scale (SAS) and Self-rating depression scale (SDS) were applied to measure the negative emotion; Positive and negative emotion scale (PANAS) was used to evaluate the degree of positive negative emotions. In addition, Symptom Checklist 90 (SCL-90), Connor-Davidson Resilience Scale (CD-RISC) self-assessment scale, and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (EORTC QLQ-C30) were applied to evaluate the mental state, mental resilience, and quality of life, respectively. The adverse reactions, prognosis, and intervention satisfaction after intervention were compared between the two groups.
After intervention, the PFS scores, SAS score, SDS score, and PANAS score in the general group and intervention groups were decreased (all < 0.05), and these scores decreased more obviously in the intervention group compared with the general group (all < 0.05); The scores of each dimension in SCL-90 scale were decreased in both groups ( < 0.05), and the SCL-90 scores in the intervention group were lower than those in the general group ( < 0.05); The scores of each dimension in CD-RISC scale improved in both groups ( < 0.05), and the scores were higher in the intervention group compared with the general group ( < 0.05); The scores of EORTC QLQ-C30 scale improved in both groups ( < 0.05), and these scores were higher in the intervention groups compared with the general group ( < 0.05). In addition, the adverse reaction rate was lower, while the prognosis and nursing satisfaction were better in the intervention group than those in the general group (all < 0.05). Logistic regression analysis showed that the poor emotion and poor life quality were the risk factors of the poor prognosis (all < 0.05).
The stepwise psychological intervention can improve the psychological wellbeing and quality of life in the patients after colon cancer surgery.
探讨阶段性心理干预对结肠癌术后患者不良情绪及生活质量的影响。
回顾性收集并分析2018年1月至2022年6月在保定市第二医院收治的102例结肠癌患者的临床资料。根据干预措施，将51例接受一般干预的患者作为一般组，51例接受阶段性心理干预的患者作为干预组。采用派珀疲劳量表（PFS）评估癌症相关疲劳（CRF）程度；应用焦虑自评量表（SAS）和抑郁自评量表（SDS）测量负性情绪；采用正负性情绪量表（PANAS）评估正负性情绪程度。此外，分别应用症状自评量表90（SCL - 90）、康纳 - 戴维森心理韧性量表（CD - RISC）自评量表和欧洲癌症研究与治疗组织生活质量问卷核心30（EORTC QLQ - C30）评估心理状态、心理韧性和生活质量。比较两组干预后的不良反应、预后及干预满意度。
干预后，一般组和干预组的PFS评分、SAS评分、SDS评分及PANAS评分均降低（均P<0.05），且干预组这些评分较一般组下降更明显（均P<0.05）；两组SCL - 90量表各维度评分均降低（P<0.05），且干预组SCL - 90评分低于一般组（P<0.05）；两组CD - RISC量表各维度评分均提高（P<0.05），且干预组评分高于一般组（P<0.05）；两组EORTC QLQ - C30量表评分均提高（P<0.05），且干预组评分高于一般组（P<0.05）。此外，干预组不良反应发生率较低，而预后及护理满意度优于一般组（均P<0.05）。Logistic回归分析显示，不良情绪及生活质量差是预后不良的危险因素（均P<0.05）。
阶段性心理干预可改善结肠癌术后患者的心理健康及生活质量。
