Mandyam Saikiran, Valisekka Sai Sudha, Parghi Devam, Chirrareddy Yagnapriya, Kalluru Pavan Kumar Reddy, Ibie Nowoghomwenma C
Internal Medicine, Southeast Health Medical Center, Dothan, USA.
Internal Medicine, University of Minnesota, Minneapolis, USA.
Cureus. 2023 Jun 10;15(6):e40221. doi: 10.7759/cureus.40221. eCollection 2023 Jun.
Myxedema coma is a grave medical condition that warrants emergent medical management to avoid adverse effects and unfavorable outcomes. Intravenous thyroid hormones (T3 and T4), along with intravenous hydrocortisone and frequent vital monitoring, are the mainstays of the management of myxedema coma. The interplay between CKD and hypothyroidism is fascinating and can affect each other. It is often very difficult for physicians to differentiate between sepsis and myxedema coma, especially in the early stages. Infections and medication non-compliance are the leading causes of precipitation myxedema coma. We describe a case report presented with myxedema coma and CKD, which was successfully managed and also led to a partial reversal of CKD status.
黏液性水肿昏迷是一种严重的医疗状况，需要紧急医疗处理以避免不良反应和不良后果。静脉注射甲状腺激素（T3和T4），以及静脉注射氢化可的松和频繁的生命体征监测，是黏液性水肿昏迷治疗的主要手段。慢性肾脏病（CKD）和甲状腺功能减退之间的相互作用很有趣，且会相互影响。医生常常很难区分脓毒症和黏液性水肿昏迷，尤其是在早期阶段。感染和药物治疗不依从是引发黏液性水肿昏迷的主要原因。我们描述了一例黏液性水肿昏迷合并CKD的病例报告，该病例得到了成功治疗，且CKD状态也出现了部分逆转。
