Department of Cardiology, Mufti Mehmood Memorial Teaching Hospital, DI Khan, Pakistan.
Department of Dermatology, Benazir Bhutto Hospital, Rawalpindi, Pakistan.
Ann Noninvasive Electrocardiol. 2023 Sep;28(5):e13070. doi: 10.1111/anec.13070. Epub 2023 Jul 12.
The aim of the study was to assess the efficacy of cardiac resynchronization therapy (CRT) in patients with chemotherapy-induced cardiomyopathy (CIC).
With the increasing incidence of CIC, the association of CRT with improvement in clinical outcomes, echocardiographic parameters, and New York Heart Classification (NYHA) class was assessed through this qualitative systematic review.
The five studies included a total of 169 patients who underwent CRT after CIC, and of these, 61 (36.1%) patients were males. All studies showed an improvement in left ventricular ejection fraction (LVEF), among other echocardiographic parameters of LV volume. However, these findings are limited by short follow-up periods, small sample sizes, and the absence of a control group.
CRT was associated with improvement in all patient parameters with CIC.
本研究旨在评估心脏再同步治疗（CRT）在化疗诱导性心肌病（CIC）患者中的疗效。
随着 CIC 发病率的增加，通过定性系统评价评估了 CRT 与临床结局、超声心动图参数和纽约心功能分级（NYHA）的改善之间的关联。
这 5 项研究共纳入了 169 例在 CIC 后接受 CRT 的患者，其中 61 例（36.1%）为男性。所有研究均显示左心室射血分数（LVEF）以及左心室容积等超声心动图参数得到改善。然而，这些发现受到随访时间短、样本量小以及缺乏对照组的限制。
CRT 与 CIC 患者的所有参数改善相关。
