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肾细胞癌的保守性手术

Conservative surgery of renal cell carcinoma.

作者信息

Bazeed M A, Schärfe T, Becht E, Jurincic C, Alken P, Thüroff J W

出版信息

Eur Urol. 1986;12(4):238-43. doi: 10.1159/000472627.

DOI:10.1159/000472627
PMID:3743593
Abstract

From 1967 to 1985 conservative surgery (enucleation, n = 49; partial resection, n = 7) was performed for renal tumors in 57 patients (age 31-77, mean 54.8 years). Imperative indications for conservative surgery (n = 29) were chronic renal failure, benign pathology of contralateral kidney, functional or anatomical solitary kidney, and bilateral tumors. Elective conservative surgery (n = 28) was done for small, peripherally located lesions, in cases of uncertain malignancy and in one tumor detected by chance during stone surgery. Tumors removed for imperative indications were 2-11 cm (mean 5.8 cm) in size. In the elective group, tumor size ranged from 1 to 7 cm (mean 3.3 cm). Follow-up was 6-103 months (mean 35.8 months). In the group with imperative indications, there was 1 postoperative mortality; 18 of 29 patients are alive without evidence of disease, 2 with metastases, and 2 were reoperated conservatively for local recurrences; 1 was lost to follow-up, 2 died of metastases, and 3 died due to unrelated reasons. In the elective group all 28 patients are living free of cancer.

摘要

1967年至1985年期间,对57例肾肿瘤患者(年龄31 - 77岁,平均54.8岁)实施了保守性手术(摘除术,n = 49;部分切除术,n = 7)。保守性手术的必要指征(n = 29)包括慢性肾衰竭、对侧肾良性病变、功能性或解剖学上的孤立肾以及双侧肿瘤。选择性保守性手术(n = 28)适用于小的、位于周边的病变、恶性情况不确定的病例以及在结石手术中偶然发现的一个肿瘤。因必要指征而切除的肿瘤大小为2 - 11厘米(平均5.8厘米)。在选择性手术组中,肿瘤大小为1至7厘米(平均3.3厘米)。随访时间为6 - 103个月(平均35.8个月)。在有必要指征的组中,有1例术后死亡;29例患者中有18例存活且无疾病证据,2例有转移,2例因局部复发接受了保守性再次手术;1例失访,2例死于转移,3例因无关原因死亡。在选择性手术组中,所有28例患者均无癌生存。

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Conservative surgery of renal cell carcinoma.肾细胞癌的保守性手术
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[Minimally invasive vs. open surgical procedures in the treatment of renal cell carcinoma].[微创与开放手术治疗肾细胞癌的对比]
Urologe A. 2015 Feb;54(2):231-3. doi: 10.1007/s00120-014-3673-3.
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[Imperative nephron-sparing surgery for cases of solitary kidney/bilateral tumors: long-term results].[孤立肾/双侧肿瘤病例的急诊保肾手术:长期结果]
Urologe A. 2008 Jul;47(7):818-23. doi: 10.1007/s00120-008-1712-7.
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Nephron-sparing surgery for renal cell carcinoma.肾细胞癌的保留肾单位手术。
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Factors influencing adrenal metastasis in renal cell carcinoma.影响肾细胞癌肾上腺转移的因素。
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Should there be a size limit for elective nephron-sparing surgery?选择性保留肾单位手术是否应该有大小限制?
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