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巴西圣保罗州足月低出生体重儿死亡率的空间分布及其决定因素。

Spatial patterns of mortality in low birth weight infants at term and its determinants in the State of São Paulo, Brazil.

机构信息

Universidade Estadual de São Paulo, Postgraduate Program in Engineering - Guaratinguetá (SP), Brazil.

Universidade de Taubaté, Postgraduate Program in Environmental Sciences - Taubaté (SP), Brazil.

出版信息

Rev Bras Epidemiol. 2023 Jul 10;26:e230034. doi: 10.1590/1980-549720230034. eCollection 2023.

Abstract

OBJECTIVE

Low birth weight (LBW) is a public health problem strongly associated with infant mortality. This study aimed to identify the spatial distribution of infant mortality in newborns with LBW (750-2,500 g) at term (≥37 weeks of gestation), due to their being small for gestational age, analyzing its association with mother-related determinants, as well as to identify priority areas of mortality in the State of São Paulo, 2010-2019.

METHODS

Infant mortality rate was analyzed in the division of neonatal mortality and postneonatal mortality of newborns with LBW at term. The empirical Bayesian method smoothed the rates, the univariate Moran index was used to measure the degree of spatial association between the municipalities, and the bivariate Moran index was employed to identify the existence of a spatial association between the rates and the selected determinants. Thematic maps of excess risk and local Moran were prepared to identify spatial clusters, adopting 5% as a significance level.

RESULTS

The excess risk map showed that more than 30% of the municipalities had rates above the state rate. High-risk clusters were identified in the southwest, southeast, and east regions, mainly among more developed municipalities. The determinants of adolescent mothers, mothers over 34 years of age, low education, human development index, social vulnerability index, gross domestic product, physicians, and pediatric beds showed a significant association with the rates evaluated.

CONCLUSIONS

Priority areas and significant determinants associated with reduced mortality in newborns with LBW were identified, suggesting the need for intervention measures to achieve the Sustainable Development Goal.

摘要

目的

低出生体重(LBW)是与婴儿死亡率密切相关的公共卫生问题。本研究旨在确定因小于胎龄而足月(≥37 周妊娠)的 LBW 新生儿(750-2500 克)的婴儿死亡率的空间分布,分析其与母亲相关决定因素的关系,并确定 2010-2019 年圣保罗州的死亡重点领域。

方法

分析了新生儿死亡率和新生儿后期死亡率中 LBW 新生儿的婴儿死亡率。经验贝叶斯方法对率进行了平滑处理,使用单变量 Moran 指数来衡量各市之间的空间关联程度,并用双变量 Moran 指数来确定率与所选决定因素之间是否存在空间关联。制作了超额风险和局部 Moran 的专题地图,以识别空间聚类,采用 5%作为显著性水平。

结果

超额风险图显示,超过 30%的城市的死亡率高于州的死亡率。在西南部、东南部和东部地区发现了高风险集群,主要集中在较为发达的城市。青少年母亲、34 岁以上母亲、低教育水平、人类发展指数、社会脆弱性指数、国内生产总值、医生和儿科床位等决定因素与评估的死亡率存在显著关联。

结论

确定了与 LBW 新生儿死亡率降低相关的重点领域和显著决定因素,表明需要采取干预措施来实现可持续发展目标。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f51/10337794/8edb50f86064/1980-5497-rbepid-26-e230034-gf01.jpg

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