Little J W
Exp Neurol. 1986 Sep;93(3):510-21. doi: 10.1016/0014-4886(86)90171-8.
Implanted nerve cuff and muscle electrodes were used to serially record reflexes after spinal cord transection in cat. Recording of reflexes, in response to both sensory nerve and to mixed motor and sensory nerve stimulation, was accomplished through 2 months after cord section. Serial recording of afferent and efferent nerve volleys was achieved as well. Serial reflex changes that follow cord transection are described. Reflex amplitude to sensory nerve stimulation increased in two phases. The first increase was noted between 1 and 4 days after cord transection; the second increase was recorded between 2 and 4 weeks. These observations suggest that at least two neuronal mechanisms with distinct temporal courses mediate the appearance of spinal hyperreflexia. The animal model described may be useful for further study of the neuronal mechanisms which underlie the hyperreflexia of spinal cord injury.
在猫脊髓横断后，使用植入的神经袖套和肌肉电极连续记录反射。在脊髓横断后的2个月内，完成了对感觉神经以及混合运动和感觉神经刺激的反射记录。同时也实现了传入和传出神经冲动的连续记录。描述了脊髓横断后反射的系列变化。对感觉神经刺激的反射幅度分两个阶段增加。第一次增加在脊髓横断后1至4天被观察到；第二次增加记录在2至4周之间。这些观察结果表明，至少有两种具有不同时间进程的神经元机制介导了脊髓反射亢进的出现。所描述的动物模型可能有助于进一步研究脊髓损伤后反射亢进的神经元机制。
