Khudaverdian D N
Biull Eksp Biol Med. 1978 Dec;86(12):659-62.
Experiments were carried out on parathyroprival cats with varying degree of motor disorders. Disturbed reflex activity of the spinal cord was characterized by activation of motoneurons and the system of intercalary neurons, abatement of the phenomenon of posttetanic potentiation as well as by conductivity facilitation in the reflex arch. Marked tetany was accompanied by diminution and, in some cases, by complete absence of monosynaptic responses with enhancement of polysynaptic reflex discharges. After intravenous injection of calcium chloride the test animals showed a tendency to recovery of the reflexes recorded. It is concluded that the disordered functional state of the spinal cord segmental apparatus is mainly due to hypocalciemia and may be one of the causes of parathyroprival tetany.
对患有不同程度运动障碍的甲状旁腺切除猫进行了实验。脊髓反射活动紊乱的特征是运动神经元和中间神经元系统的激活、强直后增强现象的减弱以及反射弧中的传导易化。明显的手足搐搦伴有单突触反应的减弱,在某些情况下完全消失,同时多突触反射放电增强。静脉注射氯化钙后,受试动物表现出所记录反射恢复的趋势。得出的结论是,脊髓节段性装置的功能状态紊乱主要是由于低钙血症,可能是甲状旁腺切除后手足搐搦的原因之一。