胃泌素与胃转铁蛋白的结合。

Binding of gastrin to gastric transferrin.

作者信息

Baldwin G S, Chandler R, Weinstock J

出版信息

FEBS Lett. 1986 Sep 1;205(1):147-9. doi: 10.1016/0014-5793(86)80883-3.

Abstract

Binding of 125I-gastrin to porcine gastric transferrin has been demonstrated by covalent cross-linking with disuccinimidyl suberate. The concentration of gastrin required to reduce cross-linking by 50% was approx. 100 microM. The occurrence of both gastrin and gastric transferrin in porcine gastric mucosa and lumen suggests a novel synergistic role for the observed interaction in the uptake of dietary iron.

摘要

通过与辛二酸二琥珀酰亚胺酯进行共价交联，已证实¹²⁵I-胃泌素与猪胃转铁蛋白的结合。使交联减少50%所需的胃泌素浓度约为100微摩尔。猪胃黏膜和管腔中同时存在胃泌素和胃转铁蛋白，这表明所观察到的相互作用在膳食铁摄取中具有一种新的协同作用。