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Exploring the role of mu opioid receptors in the therapeutic potential and abuse liability of (S)-ketamine.

作者信息

Levinstein Marjorie R, Michaelides Michael

机构信息

Biobehavioral Imaging and Molecular Neuropsychopharmacology Unit, National Institute on Drug Abuse Intramural Research Program, Baltimore, MD, 21224, USA.

Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.

出版信息

Neuropsychopharmacology. 2024 Jan;49(1):315-316. doi: 10.1038/s41386-023-01652-x.

DOI:10.1038/s41386-023-01652-x
PMID:37438422
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10700302/
Abstract
摘要

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本文引用的文献

1
Mu Opioid Receptor Activation Mediates (S)-ketamine Reinforcement in Rats: Implications for Abuse Liability.μ 阿片受体激活介导（S）-氯胺酮在大鼠中的强化作用：对滥用倾向的影响。
Biol Psychiatry. 2023 Jun 15;93(12):1118-1126. doi: 10.1016/j.biopsych.2022.12.019. Epub 2022 Dec 24.
2
6-O-(2-[F]Fluoroethyl)-6-O-Desmethyl-Diprenorphine ([F]FE-DPN) Preferentially Binds to Mu Opioid Receptors In Vivo.6-O-(2-[F]氟乙基)-6-O-去甲基二丙诺啡([F]FE-DPN)在体内优先与μ阿片受体结合。
Mol Imaging Biol. 2023 Apr;25(2):384-390. doi: 10.1007/s11307-022-01767-5. Epub 2022 Aug 23.
3
Synergistic Effect of Ketamine and Buprenorphine Observed in the Treatment of Buprenorphine Precipitated Opioid Withdrawal in a Patient With Fentanyl Use.氯胺酮和丁丙诺啡在治疗芬太尼使用者丁丙诺啡诱发阿片戒断中的协同作用
J Addict Med. 2022;16(4):483-487. doi: 10.1097/ADM.0000000000000929. Epub 2021 Nov 16.
4
Pharmacological and behavioral divergence of ketamine enantiomers: implications for abuse liability.氯胺酮对映异构体的药理学和行为学差异：对滥用倾向的影响。
Mol Psychiatry. 2021 Nov;26(11):6704-6722. doi: 10.1038/s41380-021-01093-2. Epub 2021 Apr 15.
5
Stereoselective interaction of ketamine with recombinant mu, kappa, and delta opioid receptors expressed in Chinese hamster ovary cells.氯胺酮与中国仓鼠卵巢细胞中表达的重组μ、κ和δ阿片受体的立体选择性相互作用。
Anesthesiology. 1999 Jan;90(1):174-82. doi: 10.1097/00000542-199901000-00023.