Rat liver microsomal phospholipase A2 and membrane fluidity.
作者信息
Momchilova A, Petkova D, Koumanov K
出版信息
Int J Biochem. 1986;18(7):659-63. doi: 10.1016/0020-711x(86)90297-1.
PMID:3743874
Abstract
The influence of the physical state and the lipid composition on microsomal membrane-bound phospholipase A2 activity has been investigated. It was established that the decrease of membrane fluidity expressed by the alterations of the steady-state fluorescent anisotropy (rs) and the structural order parameter for DPH (SDPH) leads to augmentation of phospholipase A2 specific activity. Phosphatidylinositol is the only phospholipid having a specific activating effect on microsomal membrane-bound phospholipase A2.
摘要
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