一个关于猪、β受体阻滞剂和基因变体的故事。 - Suppr | 超能文献

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A tale of pigs, beta-blockers and genetic variants.一个关于猪、β受体阻滞剂和基因变体的故事。

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Cardiac anti-ischemic effect of metoprolol: role of beta-blockade within the ischemic region.美托洛尔的心脏抗缺血作用：β受体阻滞在缺血区域的作用

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Metoprolol, but not atenolol, reduces stress induced neuropeptide Y release in pigs.美托洛尔而非阿替洛尔可减少应激诱导的猪神经肽 Y 释放。

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Beta-blockers in heart failure: are pharmacological differences clinically important?心力衰竭中的β受体阻滞剂：药理学差异在临床上重要吗？

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Pharmacokinetics and pharmacodynamics of beta blockers in heart failure.β受体阻滞剂在心力衰竭中的药代动力学和药效学

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Local beta-adrenergic blockade does not reduce infarct size after coronary occlusion and reperfusion: a study of coronary venous retroinfusion of metoprolol.局部β-肾上腺素能阻滞不能减少冠状动脉闭塞和再灌注后的梗死面积：美托洛尔冠状动脉逆行灌注的研究

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β-Adrenergic receptor antagonists ameliorate myocyte T-tubule remodeling following myocardial infarction.β-肾上腺素能受体拮抗剂改善心肌梗死后心肌细胞 T 小管重构。

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Metoprolol exerts a non-class effect against ischaemia-reperfusion injury by abrogating exacerbated inflammation.美托洛尔通过消除加剧的炎症对缺血再灌注损伤发挥非典型效应。

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Comparison of nifedipine and metoprolol on collateral coronary blood flow in a swine model of chronic coronary obstruction and acute ischaemia during isoflurane anaesthesia.硝苯地平与美托洛尔对异氟烷麻醉下慢性冠状动脉阻塞和急性缺血猪模型冠状动脉侧支血流的比较。

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Treatment and post-treatment effects of alpha- versus beta-receptor blockers on left ventricular structure and function in essential hypertension.α受体阻滞剂与β受体阻滞剂对原发性高血压患者左心室结构和功能的治疗及治疗后效果

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The IMproving Preclinical Assessment of Cardioprotective Therapies (IMPACT): multicenter pig study on the effect of ischemic preconditioning.心脏保护疗法的临床前评估改善（IMPACT）：关于缺血预处理效果的多中心猪研究

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β3-Adrenergic receptor overexpression in cardiomyocytes preconditions mitochondria to withstand ischemia-reperfusion injury.β3-肾上腺素能受体在心肌细胞中的过度表达使线粒体能够耐受缺血再灌注损伤。

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No robust reduction of infarct size and no-reflow by metoprolol pretreatment in adult Göttingen minipigs.美托洛尔预处理对成年哥廷根小型猪的梗死面积和无复流无明显减少作用。

Basic Res Cardiol. 2023 Jun 8;118(1):23. doi: 10.1007/s00395-023-00993-4.

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Interaction of Cardiovascular Nonmodifiable Risk Factors, Comorbidities and Comedications With Ischemia/Reperfusion Injury and Cardioprotection by Pharmacological Treatments and Ischemic Conditioning.心血管不可变风险因素、合并症和合并用药与缺血/再灌注损伤的相互作用，以及药物治疗和缺血预处理的心脏保护作用。

Pharmacol Rev. 2023 Jan;75(1):159-216. doi: 10.1124/pharmrev.121.000348. Epub 2022 Dec 8.

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