Yu Chengxuan, Feng Sijia, Li Yunxia, Chen Jun
Department of Sports Medicine, Huashan Hospital, Fudan University; Sports Medicine Institute of Fudan University, Shanghai, 200040, China.
Macromol Biosci. 2023 Dec;23(12):e2300259. doi: 10.1002/mabi.202300259. Epub 2023 Jul 19.
Tendon and ligament injuries, prevalent requiring surgical intervention, significantly impact joint stability and function. Owing to excellent mechanical properties and biochemical stability, Nondegradable synthetic materials, including polyethylene terephthalate (PET) and polytetrafluoroethylene (PTFE), have demonstrated significant potential in the treatment of tendon and ligament injuries. These above materials offer substantial mechanical support, joint mobility, and tissue healing promotion of the shoulder, knee, and ankle joint. This review conclude the latest development and application of nondegradable materials such as artificial patches and ligaments in tendon and ligament injuries including rotator cuff tears (RCTs), anterior cruciate ligament (ACL) injuries, and Achilles tendon ruptures.
肌腱和韧带损伤很常见，通常需要手术干预，会对关节稳定性和功能产生重大影响。由于具有出色的机械性能和生化稳定性，包括聚对苯二甲酸乙二酯（PET）和聚四氟乙烯（PTFE）在内的不可降解合成材料在肌腱和韧带损伤治疗中已显示出巨大潜力。上述这些材料为肩部、膝盖和踝关节提供了强大的机械支撑、关节活动度并促进组织愈合。本综述总结了人工补片和韧带等不可降解材料在肌腱和韧带损伤（包括肩袖撕裂、前交叉韧带损伤和跟腱断裂）中的最新发展及应用情况。
