Fleg J L
Geriatrics. 1986 Sep;41(9):71-3, 76-8, 81.
The deleterious effects of prolonged bedrest on aerobic capacity, mineral balance, and various metabolic processes have been amply demonstrated. Since these functions are already compromised by aging per se, complete or prolonged bedrest should be avoided in geriatric cardiac patients if at all possible, regardless of their specific diagnosis. Diuretics are still the mainstay therapy for CHF. For elderly patients with mild CHF and preserved renal function, a thiazide rather than a loop diuretic appears preferable, due to more gentle diuresis and lower frequency of side effects.
长期卧床休息对有氧能力、矿物质平衡和各种代谢过程的有害影响已得到充分证实。由于这些功能本身就会因衰老而受损,所以老年心脏病患者应尽可能避免完全卧床或长期卧床,无论其具体诊断如何。利尿剂仍然是治疗心力衰竭的主要疗法。对于轻度心力衰竭且肾功能正常的老年患者,噻嗪类利尿剂而非袢利尿剂似乎更可取,因为其利尿作用更温和,副作用发生率更低。