Hassan Mohamed Sheikh, Mire Waberi Mohamud, Osman Sidow Nor, Hassan Mohamed Omar, Akyüz Hakan, Ahmed Abdi Ishak, Bashir Ahmed Muhammad, Abdirahman Ahmed Said
Department of Neurology, Mogadishu Somali Turkish Training and Research Hospital, Mogadishu, Somalia.
Department of Cardiology, Mogadishu Somali Turkish Training and Research Hospital, Mogadishu, Somalia.
Int J Gen Med. 2023 Jul 7;16:2887-2895. doi: 10.2147/IJGM.S414014. eCollection 2023.
The etiological investigation of the potential cardiac source of acute ischemic stroke is important for the secondary prevention of recurrent and future embolization. Transthoracic echocardiography is one of the most useful investigations for the assessment of the potential cardiac etiology of ischemic stroke. Our aim is to evaluate echocardiographic findings in patients with acute ischemic stroke admitted to a tertiary care hospital in Mogadishu, Somalia.
This was a retrospective observational study conducted in the neurology department of a tertiary care hospital in Mogadishu, Somalia. We enrolled 315 patients with acute ischemic stroke admitted to the hospital who had undergone transthoracic echocardiography between March 2019 and March 2022. We analyzed transthoracic echocardiography findings, ischemic stroke subtypes, and their associated comorbidities. We also compared the demographic data, comorbidity, and survival status of patients with abnormal echo findings to those with normal echo findings.
The mean age of patients was 62±12 years. Co-morbidities were present in about 251 (80%) of the subjects, hypertension was the most common comorbidity 99 (31.4%), followed by diabetes 72 (23%), and hyperlipidemia 37 (11.7%). Overall cardiac pathology in this study was 170 (54%). Forty-seven (15%) of the patients had low ejection fraction on transthoracic echocardiography. Male patients had slightly less left ventricular systolic dysfunction than female patients. 100 (32%) had left ventricular diastolic dysfunction (LVDD), while 113 (36%) had left ventricular hypertrophy (LVH). Patients with hypertension and diabetes had more echo abnormalities compared to others (P-values of 0.047 and 0.024, respectively). More abnormal echo findings were seen in patients who died during hospitalization than in those who survived (P = 0.008). Severe left ventricular systolic dysfunction was associated with higher mortality (P < 0.001).
Most patients with stroke in this study had abnormal echocardiograms; however, only a few had cardioembolic strokes. Abnormalities in echocardiography were more common in patients who died during hospitalization than in those who survived.
对急性缺血性卒中潜在心脏来源进行病因学调查，对于复发性及未来栓塞的二级预防至关重要。经胸超声心动图是评估缺血性卒中潜在心脏病因最有用的检查方法之一。我们的目的是评估索马里摩加迪沙一家三级医院收治的急性缺血性卒中患者的超声心动图检查结果。
这是一项在索马里摩加迪沙一家三级医院神经科进行的回顾性观察研究。我们纳入了2019年3月至2022年3月期间在该医院住院并接受经胸超声心动图检查的315例急性缺血性卒中患者。我们分析了经胸超声心动图检查结果、缺血性卒中亚型及其相关合并症。我们还比较了超声检查结果异常患者与正常患者的人口统计学数据、合并症及生存状况。
患者的平均年龄为62±12岁。约251例（80%）受试者存在合并症，高血压是最常见的合并症，有99例（31.4%），其次是糖尿病72例（23%），高脂血症37例（11.7%）。本研究中总体心脏病变为170例（54%）。47例（15%）患者经胸超声心动图显示射血分数降低。男性患者左心室收缩功能障碍略少于女性患者。100例（32%）有左心室舒张功能障碍（LVDD），而113例（36%）有左心室肥厚（LVH）。与其他患者相比，高血压和糖尿病患者的超声异常更多（P值分别为0.047和0.024）。住院期间死亡患者的超声异常发现比存活患者更多（P = 0.008）。严重左心室收缩功能障碍与较高死亡率相关（P < 0.001）。
本研究中大多数卒中患者超声心动图检查结果异常；然而，只有少数患者发生心源性栓塞性卒中。住院期间死亡患者的超声心动图异常比存活患者更常见。
