Yopa Demen Daniele Sandra, Nnanga Nga Emmanuel, Ohandza Claude Stephan, Gonsu Kamga Hortense, Kouamen Njikeu Olive Nathalie, Nguefack-Tsague Georges
Department of Public Health, University of Yaounde I, Cameroon.
Department of Pharmacology, University of Yaounde I, Cameroon.
J Public Health Afr. 2023 Apr 28;14(5):2104. doi: 10.4081/jphia.2023.2104. eCollection 2023 Apr 30.
Regulation of antibiotic prescription and consumption remains a major public health burden in low- and middle- income countries.
This study aimed to describe the antibiotic consumption of patients who had a positive antibiotic culture in a reference laboratory.
A retrospective descriptive study was conducted among 113 participants with positive antibiograms with a documented history of antibiotics intake at the Yaoundé University Teaching Hospital in Cameroon between January 2016 and June 2021. Data were stored and analyzed using the Census and Survey Processing System version 7.3 and Statistical Package for Social Science version 25.0. Descriptive statistics were used to estimate the indicators.
Of the 113 patients enrolled, 105 had a history of drug use; 56 participants (53.3%) had taken at least 2 antibiotics prior to sampling. Cephalosporins were the most consumed antibiotics (41%), followed by nitroimidazols (28.6%) and penicillins (28.6%). According to the World Health Organization classification, 55 (52.4%) took major priority antibiotics.
We are on the alert and there is an urgent need to raise awareness among clinicians and patients alike by providing them with good clinical practice guidelines.
在低收入和中等收入国家,抗生素处方和使用的管控仍然是一项重大的公共卫生负担。
本研究旨在描述在一家参考实验室中抗生素培养呈阳性的患者的抗生素使用情况。
对2016年1月至2021年6月期间在喀麦隆雅温得大学教学医院的113名抗生素药敏试验呈阳性且有抗生素摄入记录史的参与者进行了一项回顾性描述性研究。数据使用人口普查和调查处理系统7.3版以及社会科学统计软件包25.0版进行存储和分析。使用描述性统计来估计各项指标。
在纳入的113名患者中,105名有用药史;56名参与者(53.3%)在采样前至少服用过2种抗生素。头孢菌素是使用最多的抗生素(41%),其次是硝基咪唑类(28.6%)和青霉素类(28.6%)。根据世界卫生组织的分类,55名(52.4%)患者使用了重点优先抗生素。
我们需保持警惕,迫切需要通过为临床医生和患者提供良好的临床实践指南来提高他们的认识。