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Identifying the Right Target for New Drugs in Acute Kidney Injury: A Long Way Off?

作者信息

Doi Kent

机构信息

Department of Emergency and Critical Care Medicine, The University of Tokyo Graduate School of Medicine, Japan.

出版信息

Kidney Int Rep. 2023 May 31;8(7):1287-1289. doi: 10.1016/j.ekir.2023.05.025. eCollection 2023 Jul.

DOI:10.1016/j.ekir.2023.05.025
PMID:37441491
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10334450/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac97/10334450/04775b17719c/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac97/10334450/04775b17719c/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac97/10334450/04775b17719c/gr1.jpg

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本文引用的文献

1
The Effects of Peroxisome Proliferator-Activated Receptor-Delta Modulator ASP1128 in Patients at Risk for Acute Kidney Injury Following Cardiac Surgery.过氧化物酶体增殖物激活受体δ调节剂ASP1128对心脏手术后急性肾损伤高危患者的影响。
Kidney Int Rep. 2023 Apr 8;8(7):1407-1416. doi: 10.1016/j.ekir.2023.04.004. eCollection 2023 Jul.
2
Temporal change in characteristics and outcomes of acute kidney injury on renal replacement therapy in intensive care units: analysis of a nationwide administrative database in Japan, 2007-2016.急性肾损伤在重症监护病房行肾脏替代治疗的特征和结局的时间变化：日本全国行政数据库的分析，2007-2016 年。
Crit Care. 2019 May 15;23(1):172. doi: 10.1186/s13054-019-2468-8.
3
Prevention of cardiac surgery-associated AKI by implementing the KDIGO guidelines in high risk patients identified by biomarkers: the PrevAKI randomized controlled trial.
通过在生物标志物识别的高危患者中实施 KDIGO 指南预防心脏手术相关 AKI：PrevAKI 随机对照试验。
Intensive Care Med. 2017 Nov;43(11):1551-1561. doi: 10.1007/s00134-016-4670-3. Epub 2017 Jan 21.
4
Discovery and validation of cell cycle arrest biomarkers in human acute kidney injury.人类急性肾损伤中细胞周期阻滞生物标志物的发现与验证
Crit Care. 2013 Feb 6;17(1):R25. doi: 10.1186/cc12503.
5
Pharmacologic treatment of acute kidney injury: why drugs haven't worked and what is on the horizon.急性肾损伤的药物治疗：为何药物不起作用以及未来的发展方向
Clin J Am Soc Nephrol. 2007 Mar;2(2):356-65. doi: 10.2215/CJN.03280906. Epub 2007 Jan 17.