[各种肝脏疾病患者的肝脏谷草转氨酶和谷丙转氨酶活性——尤其是酒精性肝病]
[Hepatic GOT and GPT activities in patients with various liver diseases--especially alcoholic liver disease].
作者信息
Takahashi A, Sekiya C, Yazaki Y, Ono M, Sato H, Hasebe C, Ishikawa Y, Okuno K, Yamada M, Namiki M
出版信息
Hokkaido Igaku Zasshi. 1986 May;61(3):431-6.
GOT and GPT activities were measured in percutaneous needle biopsy specimens of human liver tissue from 98 cases including normal subjects and patients with various liver diseases. Hepatic GOT activity was markedly decreased in liver tissue of patients with nonalcoholic liver cirrhosis. Hepatic GPT activity was markedly decreased in liver tissue of patients with alcoholic liver cirrhosis. The GOT/GPT ratio in liver tissue was increased in patients with alcoholic liver cirrhosis (5.32 +/- 2.03) and alcoholic liver disease (4.78 +/- 2.43). The increased SGOT/SGPT ratio in patients with alcoholic liver disease is due to primarily to the increased LGOT/LGPT ratio.
在98例包括正常受试者和各种肝病患者的人肝组织经皮针吸活检标本中测定了谷草转氨酶（GOT）和谷丙转氨酶（GPT）活性。非酒精性肝硬化患者肝组织中的肝GOT活性显著降低。酒精性肝硬化患者肝组织中的肝GPT活性显著降低。酒精性肝硬化患者（5.32±2.03）和酒精性肝病患者（4.78±2.43）肝组织中的GOT/GPT比值升高。酒精性肝病患者SGOT/SGPT比值升高主要是由于LGOT/LGPT比值升高。
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